H
H. Turley
Researcher at John Radcliffe Hospital
Publications - 1
Citations - 661
H. Turley is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Transactivation & Vascular endothelial growth factor A. The author has an hindex of 1, co-authored 1 publications receiving 646 citations. Previous affiliations of H. Turley include Charité.
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Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
M. S. Wiesener,H. Turley,H. Turley,William Allen,William Allen,C. Willam,C. Willam,Kai-Uwe Eckardt,Kai-Uwe Eckardt,K.L. Talks,K.L. Talks,S.M. Wood,S.M. Wood,K.C. Gatter,K.C. Gatter,A.L. Harris,A.L. Harris,Christopher W. Pugh,Christopher W. Pugh,Peter J. Ratcliffe,Peter J. Ratcliffe,P. H. Maxwell,P. H. Maxwell +22 more
TL;DR: Functional studies in a mutant cell line expressing neither HIF-1alpha nor EPAS-1 confirmed that both proteins interact with hypoxically responsive targets, but suggest target specificity with greater EPas-1 transactivation of the VEGF promoter than the LDH-A promoter.