H
Håkan Wallin
Researcher at National Institute of Occupational Health
Publications - 213
Citations - 14715
Håkan Wallin is an academic researcher from National Institute of Occupational Health. The author has contributed to research in topics: Comet assay & Cancer. The author has an hindex of 67, co-authored 210 publications receiving 13401 citations. Previous affiliations of Håkan Wallin include University of Copenhagen & Lund University.
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Journal ArticleDOI
Kupffer cells are central in the removal of nanoparticles from the organism
Evaldas Sadauskas,Håkan Wallin,Meredin Stoltenberg,Ulla Vogel,P. Doering,Agnete Larsen,Gorm Danscher +6 more
TL;DR: In inert gold nanoparticles do not penetrate cell membranes by non-endocytotic mechanisms, but are rather taken up by endocytosis; part of these tiny nanoparticles are released into the urine as a result of simple filtration in the renal glomeruli.
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Role of oxidative damage in toxicity of particulates
Peter Møller,Nicklas Raun Jacobsen,Janne K Folkmann,Pernille Høgh Danielsen,Lone Mikkelsen,Jette Gjerke Hemmingsen,Lise K. Vesterdal,Lykke Forchhammer,Håkan Wallin,Steffen Loft +9 more
TL;DR: The results indicate that oxidative stress and elevated levels of oxidatively altered biomolecules are important intermediate endpoints that may be useful markers in hazard characterization of particulates.
Journal Article
The Comet Assay as a Rapid Test in Biomonitoring Occupational Exposure to DNA-damaging Agents and Effect of Confounding Factors
TL;DR: It is argued that none of the confounding factors are unequivocally positive in the majority of the studies and recommended that age, gender, and smoking status be used as criteria for the selection of populations and that data on exercise, diet, and recent infections be registered before blood sampling.
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Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells.
Nicklas Raun Jacobsen,Giulio Pojana,Paul D. White,Peter Møller,Corey Alexander Cohn,Karen Smith Korsholm,Ulla Vogel,Antonio Marcomini,Steffen Loft,Håkan Wallin +9 more
TL;DR: It is indicated that SWCNT and C60 are less genotoxic in vitro than carbon black and diesel exhaust particles and that the mutant frequency in the cII gene was unaffected by 576 hr of exposure.
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Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice
Nicklas Raun Jacobsen,Peter Møller,Keld Alstrup Jensen,Ulla Vogel,Ole Ladefoged,Steffen Loft,Håkan Wallin +6 more
TL;DR: The data suggest that ApoE-/- model is sensitive for evaluating particle induced inflammation and shows that instillation of CB was more toxic than inhalation of a presumed similar dose with respect to inflammation in the lungs of Apo E-/- mice.