H
Hannah M. Ensor
Researcher at Newcastle University
Publications - 15
Citations - 1036
Hannah M. Ensor is an academic researcher from Newcastle University. The author has contributed to research in topics: Acute lymphocytic leukemia & Gene. The author has an hindex of 9, co-authored 14 publications receiving 943 citations. Previous affiliations of Hannah M. Ensor include Royal Victoria Infirmary.
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Journal ArticleDOI
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial
Anthony V. Moorman,Hannah M. Ensor,Sue Richards,Lucy Chilton,Claire Schwab,Sally E. Kinsey,Ajay Vora,Chris Mitchell,Christine J. Harrison +8 more
TL;DR: In this paper, the authors analyzed cytogenetic data from 1725 children with B-cell precursor acute lymphoblastic leukaemia who were included in the UK Medical Research Council ALL97/99 study and followed up for a median time of 8·2 years.
Journal ArticleDOI
A population-based cytogenetic study of adults with acute lymphoblastic leukemia.
Anthony V. Moorman,Lucy Chilton,Jennifer Wilkinson,Hannah M. Ensor,Nick Bown,Stephen J. Proctor +5 more
TL;DR: In this paper, a population-based cohort of 349 patients diagnosed during the course of 19 years in the northern part of England were investigated and the incidence of most chromosomal abnormalities varied significantly with age.
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Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial
Hannah M. Ensor,Claire Schwab,Lisa J. Russell,Sue Richards,Heather Morrison,Dino Masic,Lisa Jones,Sally E. Kinsey,Ajay Vora,Christopoher D Mitchell,Christine J. Harrison,Anthony V. Moorman +11 more
TL;DR: Patients with CRLF2-d should be classified into the intermediate cytogenetic risk group, as its effect was mediated by other risk factors such as cytogenetics and DS status.
Journal ArticleDOI
IGH@ Translocations, CRLF2 Deregulation, and Microdeletions in Adolescents and Adults With Acute Lymphoblastic Leukemia
Anthony V. Moorman,Claire Schwab,Hannah M. Ensor,Lisa J. Russell,Heather Morrison,Lisa Jones,Dino Masic,Bella Patel,Jacob M. Rowe,Martin S. Tallman,Anthony H. Goldstone,Adele K. Fielding,Christine J. Harrison +12 more
TL;DR: CRLF2-d and IGH@-t represent distinct subtypes of adolescent and adult ALL and deletions of key B-cell differentiation and cell cycle control genes are highly prevalent but vary in frequency by cytogenetic subgroup.
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Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia
Vikki Rand,Helen Parker,Lisa J. Russell,Claire Schwab,Hannah M. Ensor,Julie Irving,Lisa Jones,Dino Masic,Lynne Minto,Heather Morrison,Sarra Ryan,Hazel M. Robinson,Paul Sinclair,Anthony V. Moorman,Jonathan C. Strefford,Christine J. Harrison +15 more
TL;DR: This study has provided evidence that chromosome 21 instability is the only anomaly among those so far investigated that is common to all iAMP21 patients, and therefore the initiating event is likely to be found among the complex structural rearrangements of this abnormal chromosome.