H
Hans Geir Eiken
Researcher at Haukeland University Hospital
Publications - 104
Citations - 3149
Hans Geir Eiken is an academic researcher from Haukeland University Hospital. The author has contributed to research in topics: Population & Ursus. The author has an hindex of 33, co-authored 100 publications receiving 2961 citations. Previous affiliations of Hans Geir Eiken include Baylor College of Medicine & University of Bergen.
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Journal ArticleDOI
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure.
Jan Kristian Damås,Hans Geir Eiken,Erik Øie,Vigdis Bjerkeli,Arne Yndestad,Thor Ueland,Theis Tønnessen,Odd Geiran,Halfdan Aass,Svein Simonsen,Geir Christensen,Stig S. Frøland,Håvard Attramadal,Lars Gullestad,Pål Aukrust +14 more
TL;DR: The present study demonstrates for the first time Chemokine and chemokine receptor gene expression and protein localisation in the human myocardium, introducing a new family of mediators with potentially important effects on the myocardia.
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Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme.
Aurora Martinez,Per M. Knappskog,Sigridur Olafsdottir,Anne P. Døskeland,Hans Geir Eiken,Randi M. Svebak,M Bozzini,Jaran Apold,Torgeir Flatmark +8 more
TL;DR: The recombinant hPAH, recovered in soluble forms, revealed a high specific activity even in crude extracts and was detected as a homogeneous band by Western-blot analysis using affinity-purified polyclonal rabbit anti-(rat PAH) antibodies.
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Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects.
Jan Kristian Damås,Torgun Wæhre,Arne Yndestad,Thor Ueland,Fredrik Müller,Hans Geir Eiken,Are Martin Holm,Bente Halvorsen,Stig S. Frøland,Lars Gullestad,Pål Aukrust +10 more
TL;DR: Findings suggest that stromal cell–derived factor (SDF-1&agr;), at least in high concentrations, may mediate antiinflammatory and matrix-stabilizing effects in unstable angina and therapeutic intervention that enhances that activity could potentially be beneficial in acute coronary syndromes.
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Enhanced gene expression of chemokines and their corresponding receptors in mononuclear blood cells in chronic heart failure—modulatory effect of intravenous immunoglobulin ☆
Jan Kristian Damås,Lars Gullestad,Halfdan Aass,Svein Simonsen,Jan Fjeld,Lisbeth Wikeby,Thor Ueland,Hans Geir Eiken,Stig S. Frøland,Pål Aukrust +9 more
TL;DR: The results further support a pathogenic role for chemokines in CHF and suggest that IVIg may represent a novel therapeutic approach, with the potential to improve LVEF in patients with CHF, possibly by modulatory effects on the chemokine network.
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Application of natural and amplification created restriction sites for the diagnosis of PKU mutations
TL;DR: PCR amplification, either conventional, or as site directed mutagenesis using primers with mismatched 3'-ends, followed by restriction endonuclease digestion, provides rapid, non-isotope assays of known mutations in the human phenylalanine hydroxylase gene.