P
Pål Aukrust
Researcher at Oslo University Hospital
Publications - 720
Citations - 29837
Pål Aukrust is an academic researcher from Oslo University Hospital. The author has contributed to research in topics: Inflammation & Heart failure. The author has an hindex of 76, co-authored 666 publications receiving 24620 citations. Previous affiliations of Pål Aukrust include University of Debrecen & University of Oslo.
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Journal ArticleDOI
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Hongchao Pan,Richard Peto,Ana-Maria Henao-Restrepo,Marie-Pierre Preziosi,Vasee Sathiyamoorthy,Quarraisha Abdool Karim,Marissa M. Alejandria,César Hernández García,Marie-Paule Kieny,Reza Malekzadeh,Srinivas Murthy,K. Srinath Reddy,Mirta Roses Periago,Pierre Abi Hanna,Florence Ader,Abdullah M. Al-Bader,Almonther Alhasawi,Emma Allum,Athari Alotaibi,Carlos A Alvarez-Moreno,Sheila Appadoo,Abdullah Asiri,Pål Aukrust,Andreas Barratt-Due,Samir Bellani,Mattia Branca,Heike B. C. Cappel-Porter,Nery Cerrato,Ting S. Chow,Najada Como,Joseph A. Eustace,Patricia J. Garcia,Sheela Godbole,Eduardo Gotuzzo,Laimonas Griskevicius,Rasha Hamra,Mariam Hassan,Mohamed Hassany,David Hutton,Irmansyah Irmansyah,Ligita Jancoriene,Jana Kirwan,Suresh Kumar,Peter Lennon,Gustavo Lopardo,Patrick Lydon,Nicola Magrini,Teresa Maguire,Suzana Manevska,Oriol Manuel,Sibylle McGinty,Marco T. Medina,María L. Mesa Rubio,Maria C. Miranda-Montoya,Jeremy Nel,Estevão Portela Nunes,Markus Perola,Antonio Portolés,Menaldi R. Rasmin,Aun Raza,Helen Rees,Paula P. S. Reges,Chris A Rogers,Kolawole Salami,Marina I. Salvadori,Narvina Sinani,Jonathan A C Sterne,Milena Stevanovikj,Evelina Tacconelli,Kari A.O. Tikkinen,Sven Trelle,Hala Zaid,John-Arne Røttingen,Soumya Swaminathan +73 more
TL;DR: These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.
Journal ArticleDOI
Enhanced Levels of Soluble and Membrane-Bound CD40 Ligand in Patients With Unstable Angina Possible Reflection of T Lymphocyte and Platelet Involvement in the Pathogenesis of Acute Coronary Syndromes
Pål Aukrust,Fredrik Müller,Thor Ueland,Trude Berget,Elinor Aaser,Anne Brunsvig,Nils Olav Solum,Forfang K,Stig S. Frøland,Lars Gullestad +9 more
TL;DR: This first demonstration of enhanced levels of soluble and membrane-bound forms ofCD40L in angina patients, with particularly high levels in patients with unstable angina, suggests that CD40L-CD40 interaction may play a pathogenic role in both the long-term atherosclerotic process and in the triggering and propagation of acute coronary syndromes.
Journal ArticleDOI
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
John Willy Haukeland,Jan Kristian Damås,Zbigniew Konopski,Else Marit Løberg,Terese Haaland,Ingeborg Løstegaard Goverud,Peter A. Torjesen,Kåre I. Birkeland,Kristian Bjøro,Pål Aukrust +9 more
TL;DR: The results indicate that patients with NAFLD are characterized by a low-grade systemic inflammation, and the high CCL2/MCP-1 levels in NASH might be of importance for the conversion from simple steatosis to NASH.
Journal ArticleDOI
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury
Øystein Sandanger,Trine Ranheim,Leif Erik Vinge,Leif Erik Vinge,Marte Bliksøen,Katrine Alfsnes,Alexandra Vanessa Finsen,Alexandra Vanessa Finsen,Christen P. Dahl,Christen P. Dahl,Erik T. Askevold,Erik T. Askevold,Geir Florholmen,Geir Florholmen,Geir Christensen,Geir Christensen,Katherine A. Fitzgerald,Katherine A. Fitzgerald,Egil Lien,Egil Lien,Guro Valen,Terje Espevik,Pål Aukrust,Pål Aukrust,Arne Yndestad +24 more
TL;DR: This study shows that the NLRP3 inflammasome is up-regulated in myocardial fibroblasts post-MI, and may be a significant contributor to infarct size development during ischaemia-reperfusion.
Journal ArticleDOI
Elevated Circulating Levels of C-C Chemokines in Patients With Congestive Heart Failure
Pål Aukrust,Thor Ueland,Fredrik Müller,Arne K. Andreassen,Ingvild Nordøy,Halfdan Aas,John Kjekshus,Svein Simonsen,Stig S. Frøland,Lars Gullestad +9 more
TL;DR: This first demonstration of increased circulating levels of C-C chemokines in CHF with particularly high levels in patients with severe disease may represent previously unrecognized pathogenic factors inCHF.