H
Haoze Li
Researcher at Zhengzhou University
Publications - 17
Citations - 198
Haoze Li is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 3, co-authored 4 publications receiving 87 citations.
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Journal ArticleDOI
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent.
Pengju Wang,Xiaozhu Li,Jiwei Wang,Dongling Gao,Yuenan Li,Haoze Li,Yongchao Chu,Zhongxian Zhang,Hongtao Liu,Guozhong Jiang,Zhenguo Cheng,Shengdian Wang,Jianzeng Dong,Baisui Feng,Louisa S. Chard,Nicholas R. Lemoine,Nicholas R. Lemoine,Yaohe Wang,Yaohe Wang +18 more
TL;DR: In this paper, a tumor-targeted oncolytic adenovirus (Ad-TD) was used to deliver non-secreting (ns) IL-12 to tumor cells and examine the therapeutic and toxic effects in Syrian hamster models of pancreatic cancer.
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Enhancing Penetration Ability of Semiconducting Polymer Nanoparticles for Sonodynamic Therapy of Large Solid Tumor
TL;DR: A semiconducting polymer nanoparticle (SPNC) that synergistically enhances tumor penetration and alleviates tumor hypoxia is reported for sonodynamic therapy of large solid tumors.
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A new oncolytic Vaccinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery
Jahangir Ahmed,Louisa S. Chard,Ming Yuan,Jiwei Wang,Anwen Howells,Yuenan Li,Haoze Li,Zhongxian Zhang,Shuangshuang Lu,Dongling Gao,Pengju Wang,Yongchao Chu,Chadwan Al Yaghchi,Joel L. Schwartz,Ghassan Alusi,Nicholas R. Lemoine,Yaohe Wang +16 more
TL;DR: It is reported that a novel Vaccinia virus (VV), VVΔTKΔN1L (with deletion of both thymidine kinase and N1L genes) armed with interleukin 12 (IL-12), can prolong postoperative survival when used as a neoadjuvant treatment in different murine and hamster surgical models of cancer.
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Promising xenograft animal model recapitulating the features of human pancreatic cancer.
Jinxin Miao,Jian-Yao Wang,Haoze Li,Haoran Guo,Louisa S Chard Dunmall,Zhongxian Zhang,Zhenguo Cheng,Dongling Gao,Jianzeng Dong,Zhongde Wang,Yaohe Wang +10 more
TL;DR: ZU001 hamsters engrafted with human PC cells are a superior animal model compared to immune-deficient mice and can be a valuable animal model for better understanding the molecular mechanism of tumorigenesis and metastasis and the evaluation of new drugs targeting human PC.
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A Sub-6 nm MnFe2O4-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy.
TL;DR: In this paper , a sub-6 nm MnFe2O4 conjugated with dichloroacetic acid (DCA) nanoparticle is developed to modulate tumor glucose metabolism and ATP catabolism for reversing the tumor immunosuppressive microenvironment.