H
Haruko Tanji
Researcher at Tohoku University
Publications - 13
Citations - 840
Haruko Tanji is an academic researcher from Tohoku University. The author has contributed to research in topics: Dementia & Alzheimer's disease. The author has an hindex of 9, co-authored 13 publications receiving 803 citations.
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A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients.
Koh Iwasaki,Takuma Satoh-Nakagawa,Masahiro Maruyama,Yasutake Monma,Miyako Nemoto,Naoki Tomita,Haruko Tanji,Hironori Fujiwara,Takashi Seki,Masahiko Fujii,Hiroyuki Arai,Hidetada Sasaki +11 more
TL;DR: The traditional Chinese herbal medicine Yi-Gan San improves BPSD and ADL and follow-up studies using a double-blinded, placebo-controlled design are recommended.
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Combined Analysis of CSF Tau Levels and [123I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer’s Disease
Nobuyuki Okamura,Hiroyuki Arai,Masahiro Maruyama,Makoto Higuchi,Toshifumi Matsui,Haruko Tanji,Takashi Seki,Hisao Hirai,Hiroshi Chiba,Masatoshi Itoh,Hidetada Sasaki +10 more
TL;DR: The authors constructed a new diagnostic index, the CSF-CBF index, based on CSF tau levels divided by regional cerebral blood flow (CBF) in the posterior cingulate cortex, which is useful in predicting Alzheimer's disease in subjects with mild cognitive impairment.
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Cerebrospinal Fluid Amyloid β1–42 Levels in the Mild Cognitive Impairment Stage of Alzheimer's Disease
Masahiro Maruyama,Hiroyuki Arai,Mitsunori Sugita,Haruko Tanji,Makoto Higuchi,Nobuyuki Okamura,Toshifumi Matsui,Susumu Higuchi,Sachio Matsushita,Hiroshi Yoshida,Hidetada Sasaki +10 more
TL;DR: CSF-tau and CSF-A beta(1-42) must be used as two distinct biomarkers that should be applied appropriately in clinical settings to help in detecting MCI subjects who are predicted to develop AD.
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Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease.
Masahiro Maruyama,Makoto Higuchi,Makoto Higuchi,Yoshie Takaki,Yukio Matsuba,Haruko Tanji,Miyako Nemoto,Naoki Tomita,Toshifumi Matsui,Nobuhisa Iwata,Hiroaki Mizukami,Shin-ichi Muramatsu,Keiya Ozawa,Takaomi C. Saido,Hiroyuki Arai,Hidetada Sasaki +15 more
TL;DR: A substantial reduction of cerebrospinal fluid neprilysin activity is shown in patients with AD‐converted mild cognitive impairment and early AD as compared with age‐matched control subjects, which unequivocally indicates significance of CSF‐NEP as a biochemical indicator to pursue a pathological process that involves decreased neprilyin activity and Aβ‐induced synaptic toxicity.
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Silent cerebral infarction: a potential risk for pneumonia in the elderly.
TL;DR: Silent cerebral infarction is a potential risk factor for development of pneumonia in the elderly and should be considered for further research, according to Tohoku University.