Hector Barrabin

TL;DR: The stoichiometry of phosphorylation (catalytic) sites in sarcoplasmic reticulum vesicles and SR ATPase purified by differential solubilization with deoxycholate was found to be 4.77 +/-0.4 and 6.05 +/- 0.18 nmol/mg of protein, respectively, whenosphorylation was carried out under conditions permitting 32P labeling of nearly all sites.

TL;DR: It is reported that Na+ binding at the activating site leads to cooperative, heterotropic interactions that are insensitive to K+.

TL;DR: The results show the complex 3D organization of Plasmodium and infected erythrocyte, and demonstrate the contribution of FIB-SEM for the obtainment of statistical data for an accurate interpretation of complex biological structures.

TL;DR: Tomatidine inhibited parasite growth in a dose-dependent manner and was consistent with an inhibition of 24-sterol methyltransferase, an important enzyme responsible for the methylation of sterols at the 24 position, which is an essential step in the production of ergosterol and other 24-methyl sterols.

TL;DR: In this article, the effects of gamma subunit on Na+, K+-ATPase were dose-dependent and pre-incubation-dependent, and they showed that PKA phosphorylation increased the capacity to stimulate ATP hydrolysis.