H
Heinrich Hofmann
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 196
Citations - 9113
Heinrich Hofmann is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Nanoparticle & Iron oxide nanoparticles. The author has an hindex of 47, co-authored 196 publications receiving 8338 citations. Previous affiliations of Heinrich Hofmann include École Polytechnique & École Normale Supérieure.
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Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system
TL;DR: The characteristics and applications of SPION in the biomedical sector are introduced and discussed, and superparamagnetic nanoparticles based on a core consisting of iron oxides that can be targeted through external magnets are discussed.
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Assessing the in vitro and in vivo toxicity of superparamagnetic iron oxide nanoparticles.
Morteza Mahmoudi,Morteza Mahmoudi,Morteza Mahmoudi,Heinrich Hofmann,Barbara Rothen-Rutishauser,Barbara Rothen-Rutishauser,Alke Petri-Fink +6 more
TL;DR: The following definitions for a nanoparticle (NP) and a nano-object will be used.
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Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells
TL;DR: The successful development of functionalized SPION displaying potential cellular uptake by human cancer cells depends both on the presence of amino groups on the coating shell of the nanoparticles and of its ratio to the amount of iron oxide.
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Effect of cell media on polymer coated superparamagnetic iron oxide nanoparticles (SPIONs): Colloidal stability, cytotoxicity, and cellular uptake studies
TL;DR: The data show that the choice of medium largely influences the uptake of these particles by HeLa cells, and the optimal medium is different for the different examined polymer coated SPIONs and it should be determined in each case, individually.
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Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings
TL;DR: It was found that the PVA- coated SPIONs with negative and neutral surface charge adsorbed more serum proteins than the dextran-coated SPions, which resulted in higher blood circulation time for PVA/coated NPs than theDextran/PVA/dextran ones.