H
Heinz-Jürgen Steinhoff
Researcher at University of Osnabrück
Publications - 152
Citations - 6027
Heinz-Jürgen Steinhoff is an academic researcher from University of Osnabrück. The author has contributed to research in topics: Spin label & Site-directed spin labeling. The author has an hindex of 43, co-authored 151 publications receiving 5642 citations. Previous affiliations of Heinz-Jürgen Steinhoff include University College London & Max Planck Society.
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Journal ArticleDOI
Global hairpin folding of tau in solution.
Sadasivam Jeganathan,Martin von Bergen,Henrik Brutlach,Heinz-Jürgen Steinhoff,Eckhard Mandelkow +4 more
TL;DR: The data indicate that tau retains some global folding even in its "natively unfolded" state, combined with the high flexibility of the chain.
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Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury.
Ulrike B. Hendgen-Cotta,Marc W. Merx,Sruti Shiva,Joel Schmitz,S Becher,Johann P. Klare,Heinz-Jürgen Steinhoff,Axel Goedecke,Jürgen Schrader,Mark T. Gladwin,Malte Kelm,Tienush Rassaf +11 more
TL;DR: Testing the central role of myoglobin as a functional nitrite reductase that regulates hypoxic NO• generation, controls cellular respiration, and therefore confirms a cytoprotective response to cardiac ischemia-reperfusion (I/R) injury finds that myoglobin is responsible for nitrite-dependent NO•generation and cardiomyocyte protein iron-nitrosylation.
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Spin labeling EPR
TL;DR: Continuous wave EPR spectra analyses and pulse EPR techniques are reviewed with special emphasis on applications to the sensory rhodopsin–transducer complex mediating the photophobic response of the halophilic archaeum Natronomonas pharaonis and the photosynthetic reaction center from Rhodobacter sphaeroides R26.
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Structural insights into the early steps of receptor—transducer signal transfer in archaeal phototaxis
TL;DR: Electron paramagnetic resonance‐based inter‐residue distance measurements between site‐directed spin‐labelled sites of sensory rhodopsin II and its transducer NpHtrII from Natronobacterium pharaonis revealed a 2:2 complex with 2‐fold symmetry.
Journal ArticleDOI
Determination of interspin distances between spin labels attached to insulin: comparison of electron paramagnetic resonance data with the X-ray structure
Heinz-Jürgen Steinhoff,Nicole Radzwill,W. Thevis,V. Lenz,D. Brandenburg,Alfred A. Antson,G.G. Dodson,A. Wollmer +7 more
TL;DR: The study of interspin distances between attached spin labels can be applied to obtain structural information on proteins under conditions where other methods like two-dimensional nuclear magnetic resonance spectroscopy or x-ray crystallography are not applicable.