H
Helen Cathcart
Researcher at Waterford Institute of Technology
Publications - 19
Citations - 1332
Helen Cathcart is an academic researcher from Waterford Institute of Technology. The author has contributed to research in topics: Amorphous solid & Solubility. The author has an hindex of 12, co-authored 17 publications receiving 1031 citations. Previous affiliations of Helen Cathcart include Trinity College, Dublin & University of Texas at Dallas.
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Journal ArticleDOI
Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs
TL;DR: This review attempts to address the critical molecular and thermodynamic aspects governing the physicochemical properties of amorphous solid dispersion systems and potential advantage of polymers as inert, hydrophilic, pharmaceutical carrier matrices.
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Ordered DNA wrapping switches on luminescence in single-walled nanotube dispersions.
Helen Cathcart,Valeria Nicolosi,J. Marguerite Hughes,Werner J. Blau,John M. Kelly,Susan J. Quinn,Jonathan N. Coleman +6 more
TL;DR: An extensive study of the time dependence of DNA wrapping in single-walled nanotube (SWNT) dispersions revealed a change in the system from a less-ordered to a more-ordered state, consistent with the formation of an ordered DNA coating.
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Spontaneous Debundling of Single-Walled Carbon Nanotubes in DNA-Based Dispersions
Helen Cathcart,Susan J. Quinn,Valeria Nicolosi,John M. Kelly,Werner J. Blau,Jonathan N. Coleman +5 more
TL;DR: In this article, it has been found that the primary factor controlling the nanotube bundle size distribution in the dispersion is the Nanotube concentration, which tends to decrease with decreasing concentration.
Journal ArticleDOI
Large Populations of Individual Nanotubes in Surfactant-Based Dispersions without the Need for Ultracentrifugation
Shane D. Bergin,Valeria Nicolosi,Helen Cathcart,Mustafa Lotya,David Rickard,Zhenyu Sun,Werner J. Blau,Jonathan N. Coleman +7 more
TL;DR: In this paper, stable dispersions of single-walled carbon nanotubes have been produced using the surfactant sodium dodecylbenzene sulfonate (SDBS).
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Theoretical and experimental investigation of drug-polymer interaction and miscibility and its impact on drug supersaturation in aqueous medium.
TL;DR: It has been found that drug-polymer combinations capable of hydrogen-bonding in the solution state are more effective in preventing drug crystallization compared to the drug- polymer systems without such interaction (CNZ-PVP), and DPM-PAA system outperformed all other ASDs in various stability conditions.