H
Helen Lavretsky
Researcher at Semel Institute for Neuroscience and Human Behavior
Publications - 230
Citations - 9166
Helen Lavretsky is an academic researcher from Semel Institute for Neuroscience and Human Behavior. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 46, co-authored 198 publications receiving 7690 citations. Previous affiliations of Helen Lavretsky include University of California, Los Angeles & Stanford University.
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Journal ArticleDOI
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
Gary W. Small,Linda M. Ercoli,Daniel H.S. Silverman,Sung-Cheng Huang,Scott Komo,Susan Y. Bookheimer,Helen Lavretsky,Karen J. Miller,Prabha Siddarth,Natalie L. Rasgon,John C. Mazziotta,Sanjaya Saxena,Hsiao-Ming Wu,Michael S. Mega,Jeffrey L. Cummings,Ann M. Saunders,Margaret A. Pericak-Vance,Allen D. Roses,Allen D. Roses,Jorge R. Barrio,Michael E. Phelps +20 more
TL;DR: The results indicate that the combination of cerebral metabolic rates and genetic risk factors provides a means for preclinical AD detection that will assist in response monitoring during experimental treatments.
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PET of Brain Amyloid and Tau in Mild Cognitive Impairment
Gary W. Small,Vladimir Kepe,Linda M. Ercoli,Prabha Siddarth,Susan Y. Bookheimer,Karen J. Miller,Helen Lavretsky,Alison C. Burggren,Greg M. Cole,Harry V. Vinters,Paul M. Thompson,S.C. Huang,Nagichettiar Satyamurthy,Michael E. Phelps,Jorge R. Barrio +14 more
TL;DR: FDDNP-PET scanning can differentiate persons with mild cognitive impairment from those with Alzheimer's disease and those with no cognitive impairment, and this technique is potentially useful as a noninvasive method to determine regional cerebral patterns of amyloid plaques and tau neurofibrillary tangles.
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A tune in "a minor" can "b major": a review of epidemiology, illness course, and public health implications of subthreshold depression in older adults.
TL;DR: The high prevalence and associated adverse health outcomes of late-life subthreshold depression indicate the major public health significance of this condition and suggest a need for further research on its neurobiology and treatment.
Journal ArticleDOI
Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex.
Martina Ballmaier,Arthur W. Toga,Rebecca E. Blanton,Elizabeth R. Sowell,Helen Lavretsky,Jeffrey R Peterson,Daniel Pham,Anand Kumar +7 more
TL;DR: The prominent bilateral gray matter deficits in the anterior cingulate and the gyrus rectus as well as the orbitofrontal cortex may reflect disease-specific modifications of elderly depression.