Helene Andersson Svahn

TL;DR: An overview of the current state of single-cell analysis involving droplet microfluidics is given and examples where dropletmicrofluidic can further biological understanding are offered.

TL;DR: The importance of developing 3D in vitro tissue/organ models by 3D bioprinting techniques, characterization of these models for evaluating their resemblance to native tissue, and their application in the prioritization of lead candidates, toxicity testing, and as disease/tumor models are highlighted.

TL;DR: A high-throughput method for single cell screening by microfluidic droplet sorting is applied to a whole-genome mutated yeast cell library yielding improved production hosts of secreted industrial enzymes.

TL;DR: The DLD device is demonstrated by sorting out shrunken yeast-cell containing droplets from 31% larger diameter droplets which were generated at the same time containing only media, present at a >40-fold excess, demonstrating the resolving power of droplet separation by DLD and establishing that droplets can be separated for a biological property of the droplet contents discriminated by a change of the physical properties of thedroplet.

TL;DR: A review of the state of the art in single-cell analysis involving droplet microfluidics can be found in this paper, where the authors provide an overview of the current state-of-the-art.