H
Helga Jonsdottir
Researcher at deCODE genetics
Publications - 2
Citations - 1001
Helga Jonsdottir is an academic researcher from deCODE genetics. The author has contributed to research in topics: Haplotype & Leukotriene B4. The author has an hindex of 2, co-authored 2 publications receiving 980 citations.
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Journal ArticleDOI
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
Anna Helgadottir,Andrei Manolescu,Gudmar Thorleifsson,Solveig Gretarsdottir,Helga Jonsdottir,Unnur Thorsteinsdottir,Nilesh J. Samani,Gudmundur Gudmundsson,Struan F.A. Grant,Gudmundur Thorgeirsson,Sigurlaug Sveinbjörnsdóttir,Einar M. Valdimarsson,Stefan E Matthiasson,Halldor Johannsson,Olof Gudmundsdottir,Mark E. Gurney,Jesus Sainz,Margret Thorhallsdottir,Margret B. Andresdottir,Michael L. Frigge,Eric J. Topol,Augustine Kong,Vilmundur Gudnason,Hakon Hakonarson,Jeffrey R. Gulcher,Kari Stefansson +25 more
TL;DR: It is concluded that variants of ALOX5AP are involved in the pathogenesis of both myocardial infarction and stroke by increasing leukotriene production and inflammation in the arterial wall.
Journal ArticleDOI
Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndrome.
Thorarinn Gislason,Johann Heidar Johannsson,Ásgeir Haraldsson,Berglind Ran Olafsdottir,Helga Jonsdottir,Augustine Kong,Michael L. Frigge,Guethrun M Jonsdottir,Hakon Hakonarson,Jeffrey R. Gulcher,Kari Stefansson +10 more
TL;DR: A strong familial component in OSAS is demonstrated and infants who died of SIDS may have shared some of the same susceptibility factors with OSAS, which is suggested to indicate cosegregation of these conditions in Icelandic families.