M
Margret Thorhallsdottir
Researcher at deCODE genetics
Publications - 1
Citations - 948
Margret Thorhallsdottir is an academic researcher from deCODE genetics. The author has contributed to research in topics: Haplotype & Leukotriene B4. The author has an hindex of 1, co-authored 1 publications receiving 929 citations.
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The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
Anna Helgadottir,Andrei Manolescu,Gudmar Thorleifsson,Solveig Gretarsdottir,Helga Jonsdottir,Unnur Thorsteinsdottir,Nilesh J. Samani,Gudmundur Gudmundsson,Struan F.A. Grant,Gudmundur Thorgeirsson,Sigurlaug Sveinbjörnsdóttir,Einar M. Valdimarsson,Stefan E Matthiasson,Halldor Johannsson,Olof Gudmundsdottir,Mark E. Gurney,Jesus Sainz,Margret Thorhallsdottir,Margret B. Andresdottir,Michael L. Frigge,Eric J. Topol,Augustine Kong,Vilmundur Gudnason,Hakon Hakonarson,Jeffrey R. Gulcher,Kari Stefansson +25 more
TL;DR: It is concluded that variants of ALOX5AP are involved in the pathogenesis of both myocardial infarction and stroke by increasing leukotriene production and inflammation in the arterial wall.