H
Hellen Amuguni
Researcher at Tufts University
Publications - 15
Citations - 542
Hellen Amuguni is an academic researcher from Tufts University. The author has contributed to research in topics: One Health & Medicine. The author has an hindex of 6, co-authored 10 publications receiving 378 citations.
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Journal ArticleDOI
Bacillus subtilis: a temperature resistant and needle free delivery system of immunogens.
Hellen Amuguni,Saul Tzipori +1 more
TL;DR: The use of Bacillus subtilis to express antigens that can be administered either intranasally or sublingually is providing new insights in the area of mucosal vaccines, and advances will help to accelerate the development and testing of new mucosalvaccines against many human and animal diseases.
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A One Health, participatory epidemiology assessment of anthrax (Bacillus anthracis) management in Western Uganda
TL;DR: Investigation of the impacts of anthrax on human livelihoods and the related perceptions of conservation, public health, and veterinary health efforts in the QENP area found that social pressures, the economics of poverty, and the lack of health and veterinary infrastructure highly influenced responses to disease.
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Pesticide Application Practices and Knowledge among Small-Scale Local Rice Growers and Communities in Rwanda: A Cross-Sectional Study.
Benjamin Ndayambaje,Hellen Amuguni,Jeanne Coffin-Schmitt,Nancy Sibo,Martin Ntawubizi,Elizabeth VanWormer +5 more
TL;DR: There is potential for high exposure to pesticides for farmers, their families, and animals sharing rice-growing or downstream environments and points to the need for training on safe and effective pesticide use.
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Sublingual immunization with an engineered Bacillus subtilis strain expressing tetanus toxin fragment C induces systemic and mucosal immune responses in piglets.
Hellen Amuguni,Sangun Lee,Kathryn O. Kerstein,David F. Brown,Boris R. Belitsky,John E. Herrmann,Gerald T. Keusch,Abraham L. Sonenshein,Saul Tzipori +8 more
TL;DR: This study demonstrates for the first time thatSL or IN administration is effective for inducing both systemic and mucosal responses in a piglet model, indicating that SL or IN delivery of a B. subtilis-based tetanus vaccine can be a simple, non-invasive, low cost strategy to induce immunity to tetanus.
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Operationalizing the One Health Approach in Uganda: Challenges and Opportunities
Esther Buregyeya,Edwinah Atusingwize,Peninah Nsamba,David Musoke,Irene Naigaga,John David Kabasa,Hellen Amuguni,William Bazeyo +7 more
TL;DR: Major achievements and challenges of OH implementation are presented, and urgent efforts should be made through government support to address current and related future challenges.