S
Saul Tzipori
Researcher at Tufts University
Publications - 299
Citations - 17056
Saul Tzipori is an academic researcher from Tufts University. The author has contributed to research in topics: Cryptosporidium parvum & Cryptosporidium. The author has an hindex of 70, co-authored 288 publications receiving 16108 citations. Previous affiliations of Saul Tzipori include University of Chicago & Tufts Medical Center.
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Complete genome sequence of the apicomplexan, Cryptosporidium parvum.
Mitchell S. Abrahamsen,Thomas J. Templeton,Shinichiro Enomoto,Juan E. Abrahante,Guan Zhu,Cheryl A. Lancto,Mingqi Deng,Chang Liu,Giovanni Widmer,Saul Tzipori,Gregory A. Buck,Ping Xu,Alan T. Bankier,Paul H. Dear,Bernard Anri Konfortov,Helen Spriggs,Lakshminarayan M. Iyer,Vivek Anantharaman,L. Aravind,Vivek Kapur +19 more
TL;DR: Genome analysis identifies extremely streamlined metabolic pathways and a reliance on the host for nutrients in the parasite, which lacks an apicoplast and its genome, and possesses a degenerate mitochondrion that has lost its genome.
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The genome of Cryptosporidium hominis
Ping Xu,Giovanni Widmer,Yingping Wang,Luiz S. Ozaki,João M. P. Alves,Myrna G. Serrano,Daniela Puiu,Patricio Manque,Donna E. Akiyoshi,Aaron J. Mackey,Aaron J. Mackey,William R. Pearson,Paul H. Dear,Alan T. Bankier,Darrell L. Peterson,Mitchell S. Abrahamsen,Vivek Kapur,Saul Tzipori,Gregory A. Buck +18 more
TL;DR: The eight-chromosome ∼9.2-million-base genome of C. hominis shows a striking concordance with the requirements imposed by the environmental niches the parasite inhabits, and phenotypic differences between these parasites must be due to subtle sequence divergence.
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Evidence for the shikimate pathway in apicomplexan parasites
Fiona Roberts,Fiona Roberts,Craig W. Roberts,Jennifer J. Johnson,Dennis E. Kyle,Tino Krell,John R. Coggins,Graham H. Coombs,Wilbur K. Milhous,Saul Tzipori,David J. P. Ferguson,Debopam Chakrabarti,Rima McLeod +12 more
TL;DR: The shikimate pathway is an attractive target for herbicides and antimicrobial agents because it is essential in algae, higher plants, bacteria and fungi, but absent from mammals as discussed by the authors.
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The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.
TL;DR: The complementation achieved by the EPEC locus indicates that the eae gene of EHEC and the EaeA gene of EPEC are functionally homologous.