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Henry D. Appelman

Researcher at University of Michigan

Publications -  195
Citations -  12512

Henry D. Appelman is an academic researcher from University of Michigan. The author has contributed to research in topics: Dysplasia & Barrett's esophagus. The author has an hindex of 60, co-authored 194 publications receiving 11746 citations. Previous affiliations of Henry D. Appelman include Upjohn & National Institutes of Health.

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Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

TL;DR: A classification system for the epithelial changes that occur in ulcerative colitis was developed, which should be applicable to other forms of inflammatory bowel disease as well and makes use of standardized terminology, addresses specific problem areas, and offers practical solutions.
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Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

TL;DR: The findings of this work support the original hypothesis, derived previously from mathematical modeling of crypt dynamics, that progressive colonic SC overpopulation occurs during colon tumorigenesis and drives CRC development.
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Hepatic fat fraction: MR imaging for quantitative measurement and display--early experience.

TL;DR: Results of the phantom study confirmed that the dual-flip angle algorithm can be used to correctly identify the dominant constituent, allowing depiction of 0%-100% of fat content.
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Achalasia. A morphologic study of 42 resected specimens.

TL;DR: Clinically unresponsive, surgically resected achalasia has almost total loss of ganglion cells, and widespread destruction of myenteric nerves has already occurred, and it cannot be determined whether this inflammation is a manifestation of ongoing nerve destruction or whether it is a secondary phenomenon.
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Arteriovenous Malformations of the Gastrointestinal Tract

TL;DR: During an eight-year period, 17 patients ranging in age from 7 months to 81 years were found to have arteriovenous malformations of the gastrointestinal tract complicated by major hemorrhage, and a clinical classification of AVMs was developed, based on angiographic characteristics, localization, age of the patient, and family history.