Henry Wiersma

TL;DR: In this paper, the authors found significant gender differences in mental health during the lockdown, where women experienced more depression symptoms and disorders and men experienced more anxiety symptoms and disorder stemming from the lockdown.

TL;DR: The Lifelines COVID-19 cohort as discussed by the authors was set up to assess the psychological and societal impacts of the COVID19 pandemic and investigate potential risk factors within the Lifelines prospective population cohort.

TL;DR: Data collected by the questionnaires will be used to address four aspects of the outbreak: how the COVID-19 pandemic developed in the three northern provinces of the Netherlands, which environmental risk factors predict disease susceptibility and severity, which genetic risk Factors predict disease susceptible and severity and what are the psychological and societal impacts of the crisis.

TL;DR: In this paper, the authors demonstrate that common and rare genetic diseases can be linked by studying the gene regulatory networks impacted by common disease-associated variants, and they implemented this in the downstreamer method and applied it to 44 GWAS traits and find that predicted downstream "key genes" are enriched with Mendelian disease genes.

TL;DR: The added value of KidneyNetwork is shown by applying it to kidney disease patients without a molecular diagnosis and consequently, ALG6 is proposed as candidate gene in one of these patients.