H
Hidenao Iwai
Researcher at Hamamatsu Photonics
Publications - 46
Citations - 1032
Hidenao Iwai is an academic researcher from Hamamatsu Photonics. The author has contributed to research in topics: Microscope & Interference microscopy. The author has an hindex of 8, co-authored 46 publications receiving 936 citations. Previous affiliations of Hidenao Iwai include Massachusetts Institute of Technology.
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Journal ArticleDOI
Fourier phase microscopy for investigation of biological structures and dynamics
Gabriel Popescu,Lauren P. Deflores,Joshua C. Vaughan,Kamran Badizadegan,Hidenao Iwai,Ramachandra R. Dasari,Michael S. Feld +6 more
TL;DR: By use of the Fourier decomposition of a low-coherence optical image field into two spatial components that can be controllably shifted in phase with respect to each other, a new high-transverse-resolution quantitative-phase microscope has been developed.
Journal ArticleDOI
Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity.
Mikako Ogawa,Yusuke Tomita,Yuko Nakamura,Min-Jung Lee,Sunmin Lee,Saori Tomita,Tadanobu Nagaya,Kazuhide Sato,Toyohiko Yamauchi,Hidenao Iwai,Abhishek Kumar,Timothy A.J. Haystead,Hari Shroff,Peter L. Choyke,Jane B. Trepel,Hisataka Kobayashi +15 more
TL;DR: NIR-PIT is a therapy that kills tumor cells by ICD, eliciting a host immune response against tumor, and efficiently induced by near-infrared photo-immunotherapy (NIR)-PIT that selectively kills target-cells on which antibody-photoabsorber conjugates bind and are activated by NIR light exposure.
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Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry.
Hidenao Iwai,Christopher Fang-Yen,Gabriel Popescu,Adam Wax,Adam Wax,T. Kamran Badizadegan,Ramachandra R. Dasari,Michael S. Feld +7 more
TL;DR: A quantitative phase-imaging interferometer in which phase shifting and noise cancellation are performed by an active feedback loop using a reference laser to measure phase measurement from weakly reflecting biological samples is described.
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Low-coherent quantitative phase microscope for nanometer-scale measurement of living cells morphology
TL;DR: A Linnik-type interference microscope provided with a low-coherent light source is developed to obtain topographic images of an intact cellular membrane on a nanometer scale and shows full field surface topography of cultured cells and reveals an intrinsic membrane motion of tens of nanometers.
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Label-free imaging of intracellular motility by low-coherent quantitative phase microscopy
TL;DR: The subject study demonstrates the imaging of cell activity by quantitatively assessing the motion of intracellular organelles and cell plasma membranes without any contrast agent by integrating the low-coherent interferometric technique and phase-referenced phase shifting technique.