Hideyuki Suzuki

TL;DR: In this paper, the authors combined the Invader assay with multiplex polymerase chain reaction (PCR), carried out in the presence of antibody to Taq polymerase, as well as using a novel 384-well card system that can reduce the required reaction volume.

TL;DR: A multi-directional engineering of the fungal photoreceptor Vivid is completed to develop pairs of distinct photoswitches named Magnets, engineered to recognize each other based on the electrostatic interactions, thus preventing homodimerization and enhancing light-induced heterodimerizing.

TL;DR: A light-inducible, user-defined, endogenous gene activation system based on CRISPR-Cas9 that can allow rapid and reversible targeted gene activation by light and exemplified photoactivation of multiple user- defined endogenous genes in mammalian cells is created.

TL;DR: In this article, an integrated analysis of metabolites and gene expression indicated that several genes encoding enzymes involved in starch degradation, sucrose metabolism, and the glyoxylate cycle are upregulated in rice plants exposed to cold or dehydration and that these changes are correlated with the accumulation of glucose (Glc), fructose, and sucrose.

TL;DR: This Issue is not only general to serve as a survey of recent progress in hybrid systems theory but also specific to introduce interesting and stimulating applications of hybrid systems in biology and medicine.