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Himanshu Gupta

Researcher at Auburn University

Publications -  110
Citations -  2845

Himanshu Gupta is an academic researcher from Auburn University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 27, co-authored 91 publications receiving 2441 citations. Previous affiliations of Himanshu Gupta include Anschutz Medical Campus & Hamdard University.

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Biological activities of quinoline derivatives.

TL;DR: An in depth view of work done so far on quinolines and its biological activities covering anticancer, antimycobacterial, antimicrobial, anticonvulsant, antiinflamatory and cardiovascular activities is provided.
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Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery

TL;DR: A new colloidal system, PLGA nanoparticle for sparfloxacin ophthalmic delivery was demonstrated to improve precorneal residence time and ocular penetration and the developed lyophilized nanosuspension was found to be stable for longer duration of time than the conventional marketed formulation with a good shelf life.
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Biological activities of pyrazoline derivatives--a recent development.

TL;DR: The present review provides an insight view to pyrazolines synthesis and its biological activities along with the compilation of recent patents on pyrazoline derivatives.
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Rapid Reversal of Left Ventricular Hypertrophy and Intracardiac Volume Overload in Patients With Resistant Hypertension and Hyperaldosteronism. A Prospective Clinical Study

TL;DR: It is shown that hyperaldosteronism causes intracardiac volume overload in patients with resistant hypertension in spite of conventional thiazide diuretic use and mineralocorticoid receptor blockade induces rapid regression of left ventricular hypertrophy irrespective of aldosterone status.
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Sustained Ocular Drug Delivery from a Temperature and pH Triggered Novel In Situ Gel System

TL;DR: The formulated and evaluation of an ocular delivery system of timolol maleate based on the concept of both temperature and pH-triggered in situ gelation is described, and a significant higher drug transport across corneal membrane and increased ocular retention time was observed using the developed formulation.