H
Hiroko Shike
Researcher at Penn State Milton S. Hershey Medical Center
Publications - 59
Citations - 2670
Hiroko Shike is an academic researcher from Penn State Milton S. Hershey Medical Center. The author has contributed to research in topics: Medicine & Kawasaki disease. The author has an hindex of 23, co-authored 52 publications receiving 2450 citations. Previous affiliations of Hiroko Shike include Pennsylvania State University & University of Tennessee Health Science Center.
Papers
More filters
Journal ArticleDOI
Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge
Hiroko Shike,Xavier Lauth,Mark Westerman,Vaughn Ostland,James M. Carlberg,Jon C. Van Olst,Chisato Shimizu,Philippe Bulet,Jane C. Burns +8 more
TL;DR: A novel antimicrobial peptide from the gill, bass hepcidin, is predominantly expressed in the liver and highly inducible by bacterial exposure, and indicated that the peptide is a new member of the hePCidin family.
Journal ArticleDOI
Sequelae of Kawasaki disease in adolescents and young adults
Jane C. Burns,Hiroko Shike,John B. Gordon,Alka Malhotra,Melissa Schoenwetter,Tomisaku Kawasaki +5 more
TL;DR: A history of antecedent Kawasaki disease should be sought in all young adults who present with acute myocardial infarction or sudden death, andCoronary artery aneurysms and calcification on chest radiography were unusual features in this group of patients.
Journal ArticleDOI
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass.
Xavier Lauth,Hiroko Shike,Jane C. Burns,Mark Westerman,Vaughn Ostland,James M. Carlberg,Jon C. Van Olst,Victor Nizet,Steven W. Taylor,Chisato Shimizu,Philippe Bulet +10 more
TL;DR: Moronecidin this article is a 22-residue, C-terminally amidated antimicrobial peptide from the skin and gill of hybrid striped bass.
Journal ArticleDOI
Kawasaki disease: A brief history.
Jane C. Burns,Howard I. Kushner,John F. Bastian,Hiroko Shike,Chisato Shimizu,Tomoyo Matsubara,Christena L. Turner +6 more
TL;DR: The natural history of KD reveals that coronary artery aneurysms occur as a sequela of the vasculitis in 20% to 25% of untreated children and 55% of cases occur in children <5 years old in the United States.
Journal ArticleDOI
Seasonality and temporal clustering of Kawasaki syndrome.
Jane C. Burns,Daniel R. Cayan,Daniel R. Cayan,Garrick Tong,Garrick Tong,Emelia Bainto,Christena L. Turner,Hiroko Shike,Tomisaku Kawasaki,Yosikazu Nakamura,Mayumi Yashiro,Hiroshi Yanagawa +11 more
TL;DR: Kawasaki syndrome has a pronounced seasonality in Japan that is consistent throughout the length of the Japanese archipelago andTemporal clustering of cases combined with marked seasonality suggests an environmental trigger for this clinical syndrome.