H
Hironobu Takahashi
Researcher at Tokushima Bunri University
Publications - 64
Citations - 1278
Hironobu Takahashi is an academic researcher from Tokushima Bunri University. The author has contributed to research in topics: Melia azedarach & Illicium. The author has an hindex of 21, co-authored 63 publications receiving 1156 citations. Previous affiliations of Hironobu Takahashi include Tokyo Medical and Dental University & Kaohsiung Medical University.
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Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase.
TL;DR: It is reported that green tea catechins inhibit this viral endonuclease activity and that their galloyl group is important for their function, making it possible to refine and optimize catechin-based drug design more readily for stability.
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Synthesis and neuroprotective activity of bergenin derivatives with antioxidant activity.
TL;DR: The most potent one is norbergenin 11-caproate, which not only exhibits stronger antioxidant activity than that of catechin but also prevents neuronal death at 10 microM on the primary culture of rat cortical neurons in DMEM supplemented with N2.
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De Novo Sequencing and Transcriptome Analysis of the Central Nervous System of Mollusc Lymnaea stagnalis by Deep RNA Sequencing
Hisayo Sadamoto,Hironobu Takahashi,Taketo Okada,Hiromichi Kenmoku,Masao Toyota,Yoshinori Asakawa +5 more
TL;DR: The results demonstrated that about 20,000 sequences had significant similarity to the reported sequences using a cutoff value of 1e-6, and showed the lack of molluscan sequences in the public databases, and allowed us to identify a large number of new transcripts in Lymnaea and mollUScan species.
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Triterpene and flavanone glycoside from Rhododendron simsii.
TL;DR: Antioxidative substances isolated from the leaves of Rhododendron simsii were a triterpene and flavanone glycoside and their structures were characterized as 19,24-dihydroxyurs-12-en-3-one-28-oic acid and 7-O-beta-D-apiofuranosyl-(1-->6)-beta- D-glucopyranosylmatteucinol by spectroscopic analysis.
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New ring C-seco limonoids from Brazilian Melia azedarach and their cytotoxic activity.
Honglei Zhou,Atsuko Hamazaki,José D. Fontana,Hironobu Takahashi,Tomoyuki Esumi,Carolina Bueno Wandscheer,Hiroaki Tsujimoto,Yoshiyasu Fukuyama +7 more
TL;DR: A methanol extract of the ripe fruits of Melia azedarach collected in Curitiba, Parana, Brazil, afforded seven new ring C-seco limonoid together with three known limonoids, which exhibited significant inhibitory activity against HeLa S3 cancer cells and weak cytotoxicity.