H
Hiroshi Hirota
Researcher at Nihon University
Publications - 208
Citations - 5105
Hiroshi Hirota is an academic researcher from Nihon University. The author has contributed to research in topics: Total synthesis & Indole test. The author has an hindex of 42, co-authored 208 publications receiving 4767 citations. Previous affiliations of Hiroshi Hirota include Yokohama City University & Chiba University.
Papers
More filters
Journal ArticleDOI
Zinc suppresses Th17 development via inhibition of STAT3 activation.
Chika Kitabayashi,Toshiyuki Fukada,Minoru Kanamoto,Wakana Ohashi,Shintaro Hojyo,Toru Atsumi,Naoko Ueda,Ichiro Azuma,Hiroshi Hirota,Masaaki Murakami,Toshio Hirano +10 more
TL;DR: It is shown that Zn suppresses T( h)17-mediated autoimmune diseases at lest in part by inhibiting the development of T(h)17 cells via attenuating STAT3 activation, which is a critical step for T(n)17 development.
Journal ArticleDOI
Evaluations of molecular docking programs for virtual screening.
TL;DR: While each docking program has some merit over the other docking programs in some aspects, DOCK showed an unexpectedly better screening performance in the enrichment rates, and several recommendations were made to enhance the screening performances of the docking programs.
Journal ArticleDOI
Terpenoids with antifouling activity against barnacle larvae from the marine sponge Acanthella cavernosa
TL;DR: In this paper, 14 terpenoids, including six new compounds, have been isolated from the marine sponge Acanthella cavernosa collected off Hachijo-jima Island.
Journal ArticleDOI
Bioactive marine metabolites. Part 35. Cytotoxic metabolites of the marine sponge Mycale adhaerens Lambe
Journal ArticleDOI
Haliclamines A and B, cytotoxic macrocyclic alkaloids from a sponge of the genus Haliclona
TL;DR: In this paper, two cytotoxic alkaloids, haliclamines A and B, have been isolated from a sponge Haliclona sp., and their structures were elucidated mainly by spectroscopic analyses including extensive 2D NMR experiments.