H
Hiroshi Yamamoto
Researcher at Ajinomoto
Publications - 50
Citations - 1487
Hiroshi Yamamoto is an academic researcher from Ajinomoto. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 17, co-authored 50 publications receiving 1257 citations.
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Journal ArticleDOI
Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection
Yohei Miyagi,Masahiko Higashiyama,Akira Gochi,Makoto Akaike,Takashi Ishikawa,Takeshi Miura,Nobuhiro Saruki,Etsuro Bando,Hideki Kimura,Fumio Imamura,Masatoshi Moriyama,Ichiro Ikeda,Akihiko Chiba,Fumihiro Oshita,Akira Imaizumi,Hiroshi Yamamoto,Hiroshi Miyano,Katsuhisa Horimoto,Osamu Tochikubo,Toru Mitsushima,Minoru Yamakado,Naoyuki Okamoto +21 more
TL;DR: It is suggested that PFAA profiling has great potential for improving cancer screening and diagnosis and understanding disease pathogenesis, which involves a relatively simple plasma assay and imposes a lower physical burden on subjects when compared to existing screening methods.
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Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia, and Hypertension in Japanese Population
Minoru Yamakado,Kenji Nagao,Akira Imaizumi,Mizuki Tani,Akiko Toda,Takayuki Tanaka,Hiroko Jinzu,Hiroshi Miyano,Hiroshi Yamamoto,Takashi Daimon,Katsuhisa Horimoto,Yuko Ishizaka +11 more
TL;DR: Even after adjusting for commonly accepted multiple risk factors, these models can predict future development of diabetes, metabolic syndrome, and dyslipidemia.
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Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study
Jun Maeda,Masahiko Higashiyama,Akira Imaizumi,Tomio Nakayama,Hiroshi Yamamoto,Takashi Daimon,Minoru Yamakado,Fumio Imamura,Ken Kodama +8 more
TL;DR: This study shows that plasma amino acid profiling will be a potential screening tool for NSCLC patients regardless of disease stage or histological type.
Journal ArticleDOI
Anti-thrombotic effects and bleeding risk of AJvW-2, a monoclonal antibody against human von Willebrand factor
Shunsuke Kageyama,Hiroshi Yamamoto,Mitsuyo Nagano,Harumi Arisaka,Takashi Kayahara,Ryota Yoshimoto +5 more
TL;DR: The results suggest that AJvW‐2 is a potent inhibitor of the GPIb‐vWF interaction and a potential novel antithrombotic agent with lower bleeding risk than GPIIb/IIIa antagonists.
Journal ArticleDOI
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
Nobuyasu Fukutake,Makoto Ueno,Nobuyoshi Hiraoka,Kazuaki Shimada,Koichi Shiraishi,Nobuhiro Saruki,Toshifumi Ito,Minoru Yamakado,Nobukazu Ono,Akira Imaizumi,Shinya Kikuchi,Hiroshi Yamamoto,Kazuhiro Katayama +12 more
TL;DR: The findings suggest that the PFAA profile of PC was significantly different from that of HC, and this index is a promising biomarker for screening and diagnosis of PC.