H
Hisashi Aso
Researcher at Tohoku University
Publications - 197
Citations - 4780
Hisashi Aso is an academic researcher from Tohoku University. The author has contributed to research in topics: Immune system & Innate immune system. The author has an hindex of 35, co-authored 188 publications receiving 4038 citations. Previous affiliations of Hisashi Aso include Agricultural Research Organization, Volcani Center & Osaka University of Pharmaceutical Sciences.
Papers
More filters
Journal ArticleDOI
Adipose tissue extracellular matrix: newly organized by adipocytes during differentiation
TL;DR: In vivo under conditions permissive for adipose conversion, the production and organization of ECM, accompanied by hyperplasia and hypertrophy of precursor cells, gives rise to adipose tissue in skeletal muscle with its own ECM products.
Journal ArticleDOI
Immunobiotic Lactobacillus jensenii Elicits Anti-Inflammatory Activity in Porcine Intestinal Epithelial Cells by Modulating Negative Regulators of the Toll-Like Receptor Signaling Pathway
Tomoyuki Shimazu,Julio Villena,Masanori Tohno,Hitomi Fujie,Shoichi Hosoya,Takeshi Shimosato,Hisashi Aso,Yoshihito Suda,Yasushi Kawai,Tadao Saito,Seiya Makino,Shuji Ikegami,Hiroyuki Itoh,Haruki Kitazawa +13 more
TL;DR: The results indicated that PIE cells can be used to study the mechanisms involved in the protective activity of immunobiotics against intestinal inflammatory damage and may provide useful information for the development of new immunologically functional feeds that help to prevent inflammatory intestinal disorders, including weaning-associated intestinal inflammation.
Journal ArticleDOI
Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice
Jahidul Islam,Shoko Sato,Kouichi Watanabe,Takaya Watanabe,Ardiansyah,Keisuke Hirahara,Yukihide Aoyama,Shuhei Tomita,Hisashi Aso,Michio Komai,Hitoshi Shirakawa +10 more
TL;DR: Data suggest that tryptophan-containing diet might ameliorate DSS-induced acute colitis and regulate epithelial homeostasis through Ahr, which could serve as a promising preventive agent in the treatment of ulcerative colitis.
Journal ArticleDOI
Remarkable differences in telomere lengths among cloned cattle derived from different cell types.
Norikazu Miyashita,Kazuho Shiga,Miharu Yonai,Kanako Kaneyama,Shuji Kobayashi,Toshiyuki Kojima,Yuji Goto,Masao Kishi,Hisashi Aso,Toshiyuki Suzuki,Minoru Sakaguchi,Takashi Nagai +11 more
TL;DR: The observations indicate that cloning does not necessarily restore the telomere clock but, rather, that nuclear transfer itself may commonly trigger an elongation of telomeres, probably more or less according to donor cell type.
Journal ArticleDOI
Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line.
Masayuki Moue,Masanori Tohno,Tomoyuki Shimazu,Taketomo Kido,Hisashi Aso,Tadao Saito,Haruki Kitazawa +6 more
TL;DR: PIE induces inflammatory responses by up-regulating Th1 cytokines and chemokines in response to LPS or ETEC, suggesting that PIE is a useful cell line for studying inflammatory responses via TLR4/MD-2 in intestinal epithelial cells.