H
Hisashi Matsuda
Researcher at Kyoto Pharmaceutical University
Publications - 51
Citations - 2503
Hisashi Matsuda is an academic researcher from Kyoto Pharmaceutical University. The author has contributed to research in topics: Salacia chinensis & Triterpene. The author has an hindex of 25, co-authored 51 publications receiving 2334 citations. Previous affiliations of Hisashi Matsuda include Kindai University.
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Structural requirements of flavonoids for inhibition of protein glycation and radical scavenging activities.
TL;DR: Various flavonoids with strong AGEs formation inhibitory activity tended to exhibit strong scavenging activity for 1,1-diphenyl-2-picrylhydrazyl and superoxide anion radicals, with several exceptions.
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Salacia reticulata and Its Polyphenolic Constituents with Lipase Inhibitory and Lipolytic Activities Have Mild Antiobesity Effects in Rats
TL;DR: Polyphenolic compounds may be involved in the antiobesity effects of SRHW in rats through inhibition of fat metabolizing enzymes (PL, LPL and GPDH) and enhanced lipolysis and inhibited hormone-sensitive lipase activity in rat adipose tissue.
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Structural Requirements of Flavonoids and Related Compounds for Aldose Reductase Inhibitory Activity
TL;DR: The methanolic extracts of several natural medicines and medicinal foodstuffs were found to show an inhibitory effect on rat lens aldose reductase, and various flavonoids and related compounds were examined to clarify the structural requirements of flavonoidal activity.
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Absolute Stereostructure of Potent α-Glucosidase Inhibitor, Salacinol, with Unique Thiosugar Sulfonium Sulfate Inner Salt Structure from Salacia reticulata
TL;DR: Salacinol showed potent inhibitory activities on several alpha-glucosidases, such as maltase, sucrase, and isomaltases, and the inhibitory effects on serum glucose levels in maltose- and sucrose-loaded rats (in vivo) were found to be more potent than that of acarbose, a commercial alpha- GLUCosidase inhibitor.
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Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.
Hiroshi Shimoda,Kiyofumi Ninomiya,Norihisa Nishida,Tomoe Yoshino,Toshio Morikawa,Hisashi Matsuda,Masayuki Yoshikawa +6 more
TL;DR: The methanolic extract from the leaves of artichoke was found to suppress serum triglyceride elevation in olive oil-loaded mice and inhibition of gastric emptying was shown to be partly involved in anti-hyperlipidemic activity.