Machine Learning is the study of methods for programming computers to learn. Computers are applied to a wide range of tasks, and for most of these it is relatively easy for programmers to design and implement the necessary software. However, there are many tasks for which this is difficult or impossible. These can be divided into four general categories. First, there are problems for which there exist no human experts. For example, in modern automated manufacturing facilities, there is a need to predict machine failures before they occur by analyzing sensor readings. Because the machines are new, there are no human experts who can be interviewed by a programmer to provide the knowledge necessary to build a computer system. A machine learning system can study recorded data and subsequent machine failures and learn prediction rules. Second, there are problems where human experts exist, but where they are unable to explain their expertise. This is the case in many perceptual tasks, such as speech recognition, hand-writing recognition, and natural language understanding. Virtually all humans exhibit expert-level abilities on these tasks, but none of them can describe the detailed steps that they follow as they perform them. Fortunately, humans can provide machines with examples of the inputs and correct outputs for these tasks, so machine learning algorithms can learn to map the inputs to the outputs. Third, there are problems where phenomena are changing rapidly. In finance, for example, people would like to predict the future behavior of the stock market, of consumer purchases, or of exchange rates. These behaviors change frequently, so that even if a programmer could construct a good predictive computer program, it would need to be rewritten frequently. A learning program can relieve the programmer of this burden by constantly modifying and tuning a set of learned prediction rules. Fourth, there are applications that need to be customized for each computer user separately. Consider, for example, a program to filter unwanted electronic mail messages. Different users will need different filters. It is unreasonable to expect each user to program his or her own rules, and it is infeasible to provide every user with a software engineer to keep the rules up-to-date. A machine learning system can learn which mail messages the user rejects and maintain the filtering rules automatically. Machine learning addresses many of the same research questions as the fields of statistics, data mining, and psychology, but with differences of emphasis. Statistics focuses on understanding the phenomena that have generated the data, often with the goal of testing different hypotheses about those phenomena. Data mining seeks to find patterns in the data that are understandable by people. Psychological studies of human learning aspire to understand the mechanisms underlying the various learning behaviors exhibited by people (concept learning, skill acquisition, strategy change, etc.).

Machine learning

So far in this course we have dealt entirely with the evolution of characters that are controlled by simple Mendelian inheritance at a single locus. There are notes on the course website about gametic disequilibrium and how allele frequencies change at two loci simultaneously, but we didn’t discuss them. In every example we’ve considered we’ve imagined that we could understand something about evolution by examining the evolution of a single gene. That’s the domain of classical population genetics. For the next few weeks we’re going to be exploring a field that’s actually older than classical population genetics, although the approach we’ll be taking to it involves the use of population genetic machinery. If you know a little about the history of evolutionary biology, you may know that after the rediscovery of Mendel’s work in 1900 there was a heated debate between the “biometricians” (e.g., Galton and Pearson) and the “Mendelians” (e.g., de Vries, Correns, Bateson, and Morgan). Biometricians asserted that the really important variation in evolution didn’t follow Mendelian rules. Height, weight, skin color, and similar traits seemed to

Human biochemical genetics

XI. STRATEGIES FOR IMPROVING DIABETES CARE D iabetes is a chronic illness that requires continuing medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications. Diabetes care is complex and requires that many issues, beyond glycemic control, be addressed. A large body of evidence exists that supports a range of interventions to improve diabetes outcomes. These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care. While individual preferences, comorbidities, and other patient factors may require modification of goals, targets that are desirable for most patients with diabetes are provided. These standards are not intended to preclude more extensive evaluation and management of the patient by other specialists as needed. For more detailed information, refer to Bode (Ed.): Medical Management of Type 1 Diabetes (1), Burant (Ed): Medical Management of Type 2 Diabetes (2), and Klingensmith (Ed): Intensive Diabetes Management (3). The recommendations included are diagnostic and therapeutic actions that are known or believed to favorably affect health outcomes of patients with diabetes. A grading system (Table 1), developed by the American Diabetes Association (ADA) and modeled after existing methods, was utilized to clarify and codify the evidence that forms the basis for the recommendations. The level of evidence that supports each recommendation is listed after each recommendation using the letters A, B, C, or E.

Standards of Medical Care in Diabetes

https://minerva-access.unimelb.edu.au/bitstream/handle/11343/197439/1207.0203v1.pdf

Internet of Things (IoT): A vision, architectural elements, and future directions

Data Mining - Concepts and Techniques.

Soak n' Boost: A universal strategy to manufacture hybrid double-network hydrogels with eminent mechanical properties is developed by postformation of the chitosan microcrystalline and chain-entanglement physical networks via simple treatment of the chitosan composite hydrogels using alkaline and saline solutions. The strategy may open an avenue to fabricate multifarious double-network hydrogels for promising applications in antifouling materials, drug delivery, and tissue engineering.

A Universal Soaking Strategy to Convert Composite Hydrogels into Extremely Tough and Rapidly Recoverable Double‐Network Hydrogels

Proceedings of the 5th international conference on Parallel and Distributed Computing: applications and Technologies

Unbalanced energy consumption is an inherent problem in wireless sensor networks characterized by multihop routing and many-to-one traffic pattern, and this uneven energy dissipation can significantly reduce network lifetime. In this paper, we study the problem of maximizing network lifetime through balancing energy consumption for uniformly deployed data-gathering sensor networks. We formulate the energy consumption balancing problem as an optimal transmitting data distribution problem by combining the ideas of corona-based network division and mixed-routing strategy together with data aggregation. We first propose a localized zone-based routing scheme that guarantees balanced energy consumption among nodes within each corona. We then design an offline centralized algorithm with time complexity O(n) (n is the number of coronas) to solve the transmitting data distribution problem aimed at balancing energy consumption among nodes in different coronas. The approach for computing the optimal number of coronas in terms of maximizing network lifetime is also presented. Based on the mathematical model, an energy-balanced data gathering (EBDG) protocol is designed and the solution for extending EBDG to large-scale data-gathering sensor networks is also presented. Simulation results demonstrate that EBDG significantly outperforms conventional multihop transmission schemes, direct transmission schemes, and cluster-head rotation schemes in terms of network lifetime.

Balancing Energy Consumption to Maximize Network Lifetime in Data-Gathering Sensor Networks

Van der Waals heterostructures based on 2D layered materials have received wide attention for their multiple applications in optoelectronic devices, such as solar cells, light-emitting devices, and photodiodes. In this work, high-performance photovoltaic photodetectors based on MoTe2 /MoS2 vertical heterojunctions are demonstrated by exfoliating-restacking approach. The fundamental electric properties and band structures of the junction are revealed and analyzed. It is shown that this kind of photodetectors can operate under zero bias with high on/off ratio (>105 ) and ultralow dark current (≈3 pA). Moreover, a fast response time of 60 µs and high photoresponsivity of 46 mA W-1 are also attained at room temperature. The junctions based on 2D materials are expected to constitute the ultimate functional elements of nanoscale electronic and optoelectronic applications.

High-Performance Photovoltaic Detector Based on MoTe2 /MoS2 Van der Waals Heterostructure.

Geographic routing is an attractive localized routing scheme for wireless sensor networks (WSNs) due to its desirable scalability and efficiency. Maintaining neighborhood information for packet forwarding can achieve a high efficiency in geographic routing, but may not be appropriate for WSNs in highly dynamic scenarios where network topology changes frequently due to nodes mobility and availability. We propose a novel online routing scheme, called Energy-efficient Beaconless Geographic Routing (EBGR), which can provide loop-free, fully stateless, energy-efficient sensor-to-sink routing at a low communication overhead without the help of prior neighborhood knowledge. In EBGR, each node first calculates its ideal next-hop relay position on the straight line toward the sink based on the energy-optimal forwarding distance, and each forwarder selects the neighbor closest to its ideal next-hop relay position as the next-hop relay using the Request-To-Send/Clear-To-Send (RTS/CTS) handshaking mechanism. We establish the lower and upper bounds on hop count and the upper bound on energy consumption under EBGR for sensor-to-sink routing, assuming no packet loss and no failures in greedy forwarding. Moreover, we demonstrate that the expected total energy consumption along a route toward the sink under EBGR approaches to the lower bound with the increase of node deployment density. We also extend EBGR to lossy sensor networks to provide energy-efficient routing in the presence of unreliable communication links. Simulation results show that our scheme significantly outperforms existing protocols in wireless sensor networks with highly dynamic network topologies.

Hong Shen

Papers

A Universal Soaking Strategy to Convert Composite Hydrogels into Extremely Tough and Rapidly Recoverable Double‐Network Hydrogels

Proceedings of the 5th international conference on Parallel and Distributed Computing: applications and Technologies

Balancing Energy Consumption to Maximize Network Lifetime in Data-Gathering Sensor Networks

High-Performance Photovoltaic Detector Based on MoTe2 /MoS2 Van der Waals Heterostructure.

Energy-Efficient Beaconless Geographic Routing in Wireless Sensor Networks