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Hong Zhao

Researcher at Rutgers University

Publications -  7
Citations -  327

Hong Zhao is an academic researcher from Rutgers University. The author has contributed to research in topics: Reagent & Dimroth rearrangement. The author has an hindex of 6, co-authored 7 publications receiving 315 citations. Previous affiliations of Hong Zhao include PerkinElmer.

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A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.

TL;DR: In this article, an A.G.G tetrad was identified for the d(G-G-A-G, A-G -G, G-A -G-N) sequence in 150 mM Na(+) (or K(+)) cation solution where four symmetry-related strands align into a novel dimeric motif.
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Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA.

TL;DR: The structure of the quadruplex contains internal cavities that can potentially accommodate Na cations positioned between adjacent tetrad planes and the potential role of quadruplex formation involving G.G.C.C tetrads during the integration of the adeno-associated parvovirus into its target on human chromosome 19, both of which involve stretches of G-G- G-C sequence elements.
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Use of a 13C Atom To Differentiate Two 15N-Labeled Nucleosides. Syntheses of [15NH2]-Adenosine, [1,NH2-15N2]- and [2-13C-1,NH2-15N2]-Guanosine, and [1,7,NH2-15N3]- and [2-13C-1,7,NH2-15N3]-2‘-Deoxyguanosine

TL;DR: The first examples of the specifically 15N and 13C multilabeled nucleosides are reported, which allow the N1 and N2 15N atoms of two 15N-labeled guanines to be unambiguously differentiated in RNA and DNA fragments.
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Specific labeling approaches to guanine and adenine imino and amino proton assignments in the AMP-RNA aptamer complex.

TL;DR: This paper outlines site-specific labeling approaches to identify slowly exchanging imino(guanine) and amino (Guanine and adenine) protons in internal loop and bulge segments of compact RNA folds such as found in the AMP–RNA aptamer complex.
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Syntheses of [1,7-15N2]- and [1,7,NH2-15N3]Adenosine and 2‘-Deoxyadenosine via an N1-Alkoxy-Mediated Dimroth Rearrangement

TL;DR: In this article, it was shown that the N 1-methoxy derivatives of adenosine and 2-deoxyadenosine undergo a Dimroth rearrangement in which the intermediate N,N-dimethylamino adducts are stable compounds.