H
Hongmin Chen
Publications - 4
Citations - 330
Hongmin Chen is an academic researcher. The author has contributed to research in topics: Promoter & Gene. The author has an hindex of 3, co-authored 4 publications receiving 317 citations.
Papers
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Journal ArticleDOI
Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
Hongmin Chen,Leon Wilkins,Nazneen Aziz,Chris Cannings,David H. Wyllie,Colin D. Bingle,John J. Rogus,James D. Beck,Steven Offenbacher,Michael J. Cork,Maryam Rafie-Kolpin,Chung-Ming Hsieh,Kenneth S. Kornman,Gordon W. Duff +13 more
TL;DR: The four haplotypes that showed different contextual effects on SNP function accounted for >98% of the estimated haplotypes in Caucasian and African-American populations, which underlines the importance of understanding the haplotype structure of populations used for genetic studies.
Patent
Alpha-msh related compounds and methods of use
TL;DR: In this article, the authors proposed a method of delivering α-MSH containing peptides, α-msH analogs, and an DNA encoding αMSH and α-mssh analogs to treat diseases characterized by inflammation and/or autoimmunity.
Journal ArticleDOI
Inhibition of NF-κB activity by plasmid expressed αMSH peptide
TL;DR: Plasmid-based vectors were created that constitutively express the immunomodulatory peptide αMSH and the activity of these vectors provides tools and the impetus for testing the constructs in several animal models of chronic inflammation.
Patent
α-MSH related compounds and methods of use
TL;DR: In this article, the authors proposed a method of delivering α-MSH containing peptides, α-msH analogs, and an DNA encoding αMSH and α-mssh analogs to treat diseases characterized by inflammation and/or autoimmunity.