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Hongnan Liu

Researcher at Chinese Academy of Sciences

Publications -  41
Citations -  1298

Hongnan Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Amino acid & Gut flora. The author has an hindex of 12, co-authored 37 publications receiving 808 citations.

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Dietary Moutan Cortex Radicis Improves Serum Antioxidant Capacity and Intestinal Immunity and Alters Colonic Microbiota in Weaned Piglets.

TL;DR: Wang et al. as discussed by the authors investigated the effects of dietary Moutan cortex radicis (MCR) supplementation on pigs' antioxidant capacity and intestinal healthy, and explored whether MCR exerts positive effects via regulating NF-κB signaling pathway and intestinal microbiota.
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L-Tryptophan activates the aryl hydrocarbon receptor and induces cell cycle arrest in porcine trophectoderm cells

TL;DR: In this article, differentially expressed genes (DEGs) in porcine trophectoderm (pTr) cells were identified by quantitative reverse transcription PCR (qPCR).
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Regulation in free amino acid profile and protein synthesis pathway of growing pig skeletal muscles by low-protein diets for different time periods.

TL;DR: The results indicate that supplementing with limiting AA to the 14%CP diet is not highly effective for the pigs in restoring protein synthesis and muscle growth, whereas the 17% CP diet likely maintains the pigs' muscle mass, which were regulated by mediating AA transceptors expression, FAA profile, and activation of the mTORC1 pathway.
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Negative effects on newborn piglets caused by excess dietary tryptophan in the morning in sows

TL;DR: The results provide information on new biomarkers in serum or liver and provide novel insights into variations in the fetal liver during exogenous stimulus response and biological processes of ROS metabolism in fetuses during late pregnancy caused by a single excessive tryptophan ingestion daily in the morning.
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Advanced single-cell pooled CRISPR screening identifies C19orf53 required for cell proliferation based on mTORC1 regulators.

TL;DR: DoNick-seq as mentioned in this paper is an advanced method for facilitating gene knockout and reducing off-target activity by re-engineered two popular plasmid constructs suitable for use in pooled CRISPR screening of the single-cell transcriptome.