H
Hongsheng Tan
Researcher at Shanghai University
Publications - 70
Citations - 1125
Hongsheng Tan is an academic researcher from Shanghai University. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 18, co-authored 70 publications receiving 817 citations. Previous affiliations of Hongsheng Tan include Hong Kong Baptist University & Shanghai Jiao Tong University.
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Journal ArticleDOI
Bioassay-guided isolation of prenylated xanthones and polycyclic acylphloroglucinols from the leaves of Garcinia nujiangensis.
Xia Zhengxiang,Dan-Dan Zhang,Shuang Liang,Yuanzhi Lao,Hong Zhang,Hongsheng Tan,Shilin Chen,Xin-Hong Wang,Hong-Xi Xu +8 more
TL;DR: Isojacareubin (6) was found to be the most potent cytotoxic compound of those tested and the test substances demonstrated selectivity toward the cancer cells.
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Guttiferone K induces autophagy and sensitizes cancer cells to nutrient stress-induced cell death.
TL;DR: These data indicate that GUTK sensitizes cancer cells to nutrient stress-induced cell death though Akt/mTOR dependent autophagy pathway.
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Bioassay-Guided Isolation of Prenylated Xanthone Derivatives from the Leaves of Garcinia oligantha.
TL;DR: The inhibitory activities of these isolates against four human tumor cell lines were assayed, and compounds 1, 2, 5, 11, and 12 showed inhibitory effects on tumor cell growth, with IC50 values ranging from 2.1 to 8.6 μM.
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Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis through activating AMPK
TL;DR: It is demonstrated that Andro effectively inhibits LPS-induced inflammatory responses via AMPK activation in macrophages, whereby Andro can ameliorate DSS-induced acute colitis in mice.
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Cambogin Induces Caspase-Independent Apoptosis through the ROS/JNK Pathway and Epigenetic Regulation in Breast Cancer Cells
Kaikai Shen,Jianling Xie,Hua Wang,Hong Zhang,Mengyuan Yu,Fangfang Lu,Hongsheng Tan,Hong-Xi Xu +7 more
TL;DR: It is indicated that cambogin can induce breast adenocarcinoma cell apoptosis and therefore represents therapeutic potential for cancer treatment.