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Hongying Wu
Researcher at Peking Union Medical College
Publications - 13
Citations - 471
Hongying Wu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Lung cancer & Total body irradiation. The author has an hindex of 8, co-authored 13 publications receiving 424 citations.
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Journal ArticleDOI
Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.
Guo-Shun Xu,Hongying Wu,Junling Zhang,Deguan Li,Yueying Wang,Yingying Wang,Heng Zhang,Lu Lu,Chengcheng Li,Song Huang,Yonghua Xing,Daohong Zhou,Daohong Zhou,Aimin Meng +13 more
TL;DR: Findings demonstrate that resveratrol can protect HSCs from radiation at least in part via activation of Sirt1 and has the potential to be used as an effective therapeutic agent to ameliorate TBI-induced long-term BM injury.
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Expression and function of miRNA in postoperative radiotherapy sensitive and resistant patients of non-small cell lung cancer
Xiao-Chun Wang,Du Liqing,Li-Li Tian,Hai-Liang Wu,Xiaoyan Jiang,Heng Zhang,Deguan Li,Yueying Wang,Hongying Wu,Yi She,Qing-Fen Liu,Fei-Yue Fan,Meng Aimin +12 more
TL;DR: 12 differently expressed miRNAs were found in the radiotherapy sensitive and resistant non-small cell lung cancer samples and results showed miRNA-126 promoted non- Small Cell lung cancer cells apoptosis induced by irradiation through the PI3K-Akt pathway.
Journal ArticleDOI
Expression of miRNA-130a in Nonsmall Cell Lung Cancer
Xiao-Chun Wang,Du Liqing,Heng Zhang,Yueying Wang,Hongying Wu,Deguan Li,Yi She,Qing-Fen Liu,Fei-Yue Fan,Meng Aimin,Li-Li Tian,Hai-Liang Wu,Xiaoyan Jiang +12 more
TL;DR: It is shown, for the first time, that miRNA-130a expression is increased in nonsmall cell lung cancer (NSCLC) tissues, and data suggest that miRNAs may comprise a potential novel prognostic marker for this disease.
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Mitigating the Effects of Xuebijing Injection on Hematopoietic Cell Injury Induced by Total Body Irradiation with γ rays by Decreasing Reactive Oxygen Species Levels
Deguan Li,Lu-De Lu,Junling Zhang,Xiao-Chun Wang,Yonghua Xing,Hongying Wu,Xiangdong Yang,Zhexin Shi,Mingfeng Zhao,Saijun Fan,Aimin Meng +10 more
TL;DR: XBJ enhances the survival rate of irradiated mice and attenuates the effects of radiation on hematopoietic injury by decreasing ROS production in BM cells, indicating that XBJ may be a promising therapeutic candidate for reducing hematopolietic radiation injury.
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Increased miRNA-22 expression sensitizes esophageal squamous cell carcinoma to irradiation
TL;DR: It is demonstrated for the first time that decreased miRNA-22 expression correlates with increased radiotherapy resistance of ESCC, and that this effect is mediated, at least in part, by the Rad51 pathway.