H
Hsu Feng Lu
Researcher at Fu Jen Catholic University
Publications - 117
Citations - 4289
Hsu Feng Lu is an academic researcher from Fu Jen Catholic University. The author has contributed to research in topics: Apoptosis & Cancer cell. The author has an hindex of 35, co-authored 108 publications receiving 3774 citations. Previous affiliations of Hsu Feng Lu include Yuanpei University & China Medical University (Taiwan).
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Journal ArticleDOI
Quercetin-mediated Cell Cycle Arrest and Apoptosis Involving Activation of a Caspase Cascade through the Mitochondrial Pathway in Human Breast Cancer MCF-7 Cells
Chu Chung Chou,Jai Sing Yang,Hsu Feng Lu,Siu Wan Ip,Chyi Lo,Chih-Chung Wu,Jing Pin Lin,Nou Ying Tang,Jing Gung Chung,Ming Jen Chou,Ying Hock Teng,Dar-Ren Chen +11 more
TL;DR: It is suggested that quercetin may induce apoptosis by direct activation of the caspase cascade through the mitochondrial pathway in MCF-7 cells.
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Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells.
Su Yu Chien,Yao Chung Wu,Jing Gung Chung,Jai Sing Yang,Hsu Feng Lu,Mei Fen Tsou,Wg Wood,Shou Jen Kuo,Dar-Ren Chen +8 more
TL;DR: Findings suggest that quercetin results in human breast cancer MDA-MB-231 cell death through mitochondrial- and caspase-3-dependent pathways.
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Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells
Chi Cheng Lu,Jai Sing Yang,An Cheng Huang,Te Chun Hsia,Su Tze Chou,Chao Lin Kuo,Hsu Feng Lu,Tsung-Han Lee,W. G. Wood,Jing Gung Chung,Jing Gung Chung +10 more
TL;DR: Human liver cancer cells treated with chrysophanol exhibited a cellular pattern associated with necrosis and not apoptosis, and reductions in adenosine triphosphate levels and increases in lactate dehydrogenase activity indicated that chrysophile stimulated necrotic cell death.
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Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells.
Wen Wen Huang,Yu Jen Chiu,Ming Jen Fan,Hsu Feng Lu,Hsiu Feng Yeh,Kun Hong Li,Po-Yuan Chen,Jing Gung Chung,Jai Sing Yang +8 more
TL;DR: It is demonstrated that kaempferol significantly reduces cell viabilities of U-2 OS, HOB and 143B cells, especially U- 2 OS cells in a dose-dependent manner, but exerts low cytotoxicity on human fetal osteoblast progenitor hFOB cells.
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Rutin inhibits human leukemia tumor growth in a murine xenograft model in vivo.
Jing Pin Lin,Jai Sing Yang,Jen Jyh Lin,Kuang Chi Lai,Hsu Feng Lu,Chia Yu Ma,Rick Sai-Chuen Wu,King Chuan Wu,Fu Shin Chueh,W. Gibson Wood,Jing Gung Chung +10 more
TL;DR: Novel findings indicate that rutin inhibits tumor growth in a xenograft animal model and may be useful in treating leukemia, but much more research is needed.