H
Hua Zhou
Researcher at China Medical University (PRC)
Publications - 44
Citations - 4263
Hua Zhou is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Kidney & Acute kidney injury. The author has an hindex of 24, co-authored 37 publications receiving 3669 citations. Previous affiliations of Hua Zhou include National Institutes of Health & Hamamatsu University School of Medicine.
Papers
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Journal ArticleDOI
Exosomes from human saliva as a source of microRNA biomarkers.
Amanda Michael,Siddhartha D. Bajracharya,Peter S.T. Yuen,Hua Zhou,Robert A. Star,Gabor G. Illei,Ilias Alevizos +6 more
TL;DR: The isolation of miRNAs from easily and non-invasively obtained Salivary exosomes with subsequent characterization of the miRNA expression patterns is promising for the development of future biomarkers of the diagnosis and prognosis of various salivary gland pathologies.
Journal ArticleDOI
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery
Hua Zhou,Peter S.T. Yuen,Trairak Pisitkun,Patricia A. Gonzales,Hideo Yasuda,James W. Dear,Peter Gross,Mark A. Knepper,Robert A. Star +8 more
TL;DR: It is concluded that protease inhibitors are essential for preservation, and storage at -80 degrees C with extensive vortexing after thawing maximizes the recovery of urinary exosomes, suggesting minimal protein degradation in the urinary tract/bladder.
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Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator.
Anita Cheruvanky,Hua Zhou,Trairak Pisitkun,Jeffrey B. Kopp,Mark A. Knepper,Peter S.T. Yuen,Robert A. Star +6 more
TL;DR: This enhanced method may accelerate the translation of urinary exosomal biomarkers from bench to bedside for the diagnosis, classification, and prognostication of renal diseases.
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Exosomal Fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury.
Hua Zhou,Trairak Pisitkun,Angel Aponte,Peter S.T. Yuen,Jason D. Hoffert,Hideo Yasuda,Xuzhen Hu,Lakhmir S. Chawla,Rong-Fong Shen,Mark A. Knepper,Robert A. Star +10 more
TL;DR: Proteomic analysis of urinary exosomes can provide biomarker candidates for the diagnosis of AKI and urinary Fetuin-A might be a predictive biomarker of structural renal injury.
Journal ArticleDOI
Urinary exosomal transcription factors, a new class of biomarkers for renal disease
Hua Zhou,Anita Cheruvanky,Xuzhen Hu,Takayuki Matsumoto,Noriyuki Hiramatsu,Monique E. Cho,Alexandra Berger,Asada Leelahavanichkul,Kent Doi,Lakhmir S. Chawla,Gabor G. Illei,Jeffrey B. Kopp,James E. Balow,Howard A. Austin,Peter S.T. Yuen,Robert A. Star +15 more
TL;DR: The findings suggest that transcription factor ATF3 may provide a novel renal tubular cell biomarker for acute kidney injury while WT-1 may detect early podocyte injury.