Recent development in band engineering of binary semiconductor materials for solar driven photocatalytic hydrogen production

Smart stimuli-responsive drug delivery systems based on cyclodextrin: A review.

Fabrication strategies and surface tuning of hierarchical gold nanostructures for electrochemical detection and removal of toxic pollutants.

Well-designed Z-scheme photocatalyst of NH2-MIL-125(Ti) MOF coupled g-C3N4 with RGO mediator synthesized with a facile hydrothermal method has been investigated for stimulating photocatalytic CO2 reduction under visible light. The amino-functionalized Ti-based MOF boosted the photocatalytic efficiency due to its high surface area and porous structure. Moreover, the NH2-MIL-125(Ti) MOF has a great ability for CO2 gas adsorption. The novel RGO-linked g-C3N4/NH2-MIL-125(Ti) nanocomposite exhibited efficient photocatalytic CO2 conversion to CH4 and CO. The experimental results showed that CO was the predominant reaction product with a production of 383.79 μmol g−1 achieved after 4 h irradiation which is 5 and 2.5 times higher compared to pure g-C3N4 and zero-MOF g-C3N4-RGO composite, respectively. However, the composite also exhibited a CH4 evolution of 13.8 μmol g−1. The amino functionality provided the MOF with antenna-like reaction sites with high affinity to CO2 molecules which improved the photocatalytic reduction of CO2 towards high CO production selectivity. An effective spatial separation and transfer of photogenerated charge carriers was also obtained as a result of RGO incorporation which constructed an effective Z-scheme bridge for the transfer of charges and limiting the high recombination rate of g-C3N4. The stability analysis of the newly developed composite revealed a continuous production of CO and CH4 in multiple cycles without any obvious deactivation under visible light. This work provides a new approach for the construction of Z-scheme heterojunction composites that would be beneficial for further investigations in selective CO2 conversion to solar fuels.

Indirect Z-scheme heterojunction of NH2-MIL-125(Ti) MOF/g-C3N4 nanocomposite with RGO solid electron mediator for efficient photocatalytic CO2 reduction to CO and CH4

Mesoporous silica nanoparticles (MSNPs) are a particular example of innovative nanomaterials for the development of drug delivery systems. MSNPs have recently received more attention for biological and pharmaceutical applications due to their capability to deliver therapeutic agents. Due to their unique structure, they can function as an effective carrier for the delivery of therapeutic agents to mitigate diseases progress, reduce inflammatory responses and consequently improve cancer treatment. The potency of MSNPs for the diagnosis and management of various diseases has been studied. This literature review will take an in-depth look into the properties of various types of MSNPs (e.g. shape, particle and pore size, surface area, pore volume and surface functionalisation), and discuss their characteristics, in terms of cellular uptake, drug delivery and release. MSNPs will then be discussed in terms of their therapeutic applications (passive and active tumour targeting, theranostics, biosensing and immunostimulative), biocompatibility and safety issues. Also, emerging trends and expected future advancements of this carrier will be provided.

Mesoporous silica nanoparticles: synthesis methods and their therapeutic use-recent advances.

Ultrasonic-microwave assisted synthesis of GO/g-C3N4 composites for efficient photocatalytic H2 evolution

With the aim to find new compounds with high antifungal activity, 21 4-amino-5-substituted-1,2,4-triazole Schiff bases (2a - 2g, 3a - 3g, and 4a - 4g) were designed and synthesized. Their antifungal activities against Pythium solani, Gibberlla nicotiancola, Fusarium oxysporium f. sp. niveum, Gibberlla saubinetii, Alternaria iycopersici, Phytophthora capsici, Physalospora piricola, Cercospora arachidicola hori, and Fusarium oxysporium f. sp. cucumber were tested, parts of the compounds exhibited excellent antifungal activity. This research provides useful information for further study of antifungal agents.

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

A two-photon multi-emissive fluorescent probe for discrimination of Cys and Hcy/GSH via an aromatic substitution-rearrangement.

IDH1 mutations occur in about 20-30% of gliomas and are a promising target for the treatment of cancer. In the present study, the performance of aIDH1R132H was verified via glide-docking-based virtual screening. On the basis of the two crystal structures (5TQH and 6B0Z) with the best discriminating ability to identify IDH1R132H inhibitors from a decoy set, a docking-based virtual screening strategy was employed for identifying new IDH1R132H inhibitors. In the end, 57 structurally diverse compounds were reserved and evaluated through experimental tests, and 10 of them showed substantial activity in targeting IDH1R132H (IC50 < 50 μM). Molecular docking technology showed that L806-0255, V015-1671, and AQ-714/41674992 could bind to the binding pocket composed of hydrophobic residues. These findings indicate that L806-0255, V015-1671, and AQ-714/41674992 have the potential as lead compounds for the treatment of IDH1-mutated gliomas through further optimization.

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Hui Guo

Papers

Ultrasonic-microwave assisted synthesis of GO/g-C3N4 composites for efficient photocatalytic H2 evolution

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

A two-photon multi-emissive fluorescent probe for discrimination of Cys and Hcy/GSH via an aromatic substitution-rearrangement.

Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening.

Quantitative measurement of carbon isotopic composition in CO2 gas reservoir by Micro-Laser Raman spectroscopy.