H
Huijuan Wu
Researcher at Fudan University
Publications - 34
Citations - 615
Huijuan Wu is an academic researcher from Fudan University. The author has contributed to research in topics: Podocyte & Decorin. The author has an hindex of 9, co-authored 26 publications receiving 334 citations. Previous affiliations of Huijuan Wu include Vanderbilt University Medical Center & Chinese Ministry of Education.
Papers
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Journal ArticleDOI
AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype.
Huijuan Wu,Huijuan Wu,Christopher P. Larsen,Cesar F. Hernandez-Arroyo,M. Mohamed,Tiffany Caza,Moh’d A. Sharshir,Asim Chughtai,Liping Xie,Juan M Gimenez,T. Sandow,Mark A Lusco,Haichun Yang,Ellen Acheampong,Ivy A. Rosales,Robert B. Colvin,Agnes B. Fogo,Juan Carlos Q. Velez,Juan Carlos Q. Velez +18 more
TL;DR: Collapsing glomerulopathy in black patients with COVID-19 was associated with high-risk APOL1 variants, suggesting a possible alternative mechanism: a "two-hit" combination of genetic predisposition and cytokine-mediated host response to SARS-CoV-2 infection.
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Classification and Differential Diagnosis of Diabetic Nephropathy.
TL;DR: Applications and evaluations using Tervaert classification and indications for renal biopsy are summarized in this review according to recent studies and differential diagnosis with another nodular glomerulopathy and the situation that a typical DN superimposed with a nondiabetic renal disease (NDRD) are discussed and concluded.
Journal ArticleDOI
UCH-L1 expression of podocytes in diseased glomeruli and in vitro
Yuan Liu,Jiajing Wu,Huijuan Wu,Tianzhan Wang,Hualei Gan,Xin Zhang,Ye Liu,Ruixi Li,Zhonghua Zhao,Qi Chen,Mu-yi Guo,Zhigang Zhang,Zhigang Zhang +12 more
TL;DR: The expression of UCH‐L1 may be associated with the regeneration of podocytes as a repair response to immunocomplex‐mediated injury and its expression can be increased in these immunocom complex‐mediated nephrites.
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High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway.
Yuyin Xu,Hongyang Gao,Yuan Hu,Yili Fang,Chenyang Qi,Huang Jiebo,Cai Xiaofan,Huijuan Wu,Xiaoqiang Ding,Zhigang Zhang +9 more
TL;DR: Data suggested that necroptosis may have more effect on the loss of podocytes than apoptosis in DN with the regulation of UCHL1, and inhibiting UCHL 1 to downregulate the RIPK1/RIPK3 pathway may be a novel strategy to protect the podocytes in DN patients.
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Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI.
Zhihuang Zheng,Zhihuang Zheng,Chuanlei Li,Guangze Shao,Jinqing Li,Kexin Xu,Zhonghua Zhao,Zhigang Zhang,Jun Liu,Huijuan Wu +9 more
TL;DR: In this paper, the role of YAP in AKI-induced chronic inflammation was investigated, and it was shown that tubular YAP activation with maladaptive repair exacerbates renal inflammation probably via promoting MCP-1 production.