H
Hung-Yu Lin
Researcher at Memorial Hospital of South Bend
Publications - 41
Citations - 899
Hung-Yu Lin is an academic researcher from Memorial Hospital of South Bend. The author has contributed to research in topics: Mitochondrion & Medicine. The author has an hindex of 13, co-authored 31 publications receiving 515 citations. Previous affiliations of Hung-Yu Lin include National Sun Yat-sen University & National Chung Hsing University.
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Journal ArticleDOI
Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy
Tsu-Kung Lin,Shang-Der Chen,Yao-Chung Chuang,Hung-Yu Lin,Chi-Ren Huang,Jiin-Haur Chuang,Pei-Wen Wang,Sheng-Teng Huang,Mao-Meng Tiao,Jin-Bor Chen,Chia-Wei Liou +10 more
TL;DR: Resveratrol induces HO-1 expression and prevents dopaminergic cell death by regulating autophagic flux; thus protecting against rotenone-induced neuronal apoptosis, and validating the hypothesis ofHO-1 dependent autophagy in preventing neuronal death in the in vitro PD model.
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Mitochondrial transfer from Wharton's jelly-derived mesenchymal stem cells to mitochondria-defective cells recaptures impaired mitochondrial function.
Hung-Yu Lin,Chia-Wei Liou,Shang-Der Chen,Te-Yao Hsu,Jiin-Haur Chuang,Pei-Wen Wang,Sheng-Teng Huang,Mao-Meng Tiao,Jin-Bor Chen,Tsu-Kung Lin,Yao-Chung Chuang +10 more
TL;DR: It is suggested that Wharton's jelly-derived MSCs may serve as a potential therapeutic strategy for diseases linked to mitochondrial dysfunction through the donation of healthy mitochondria to cells with genetic mitochondrial defects.
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The Overcrowded Crossroads: Mitochondria, Alpha-Synuclein, and the Endo-Lysosomal System Interaction in Parkinson's Disease.
Kai-Jung Lin,Kai-Lieh Lin,Shang-Der Chen,Chia-Wei Liou,Yao-Chung Chuang,Hung-Yu Lin,Tsu-Kung Lin +6 more
TL;DR: This review will analyze the biological functions and interactions between mitochondria, α-syn, and the endo-lysosomal system in the pathogenesis of PD.
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MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice
TL;DR: The results demonstrated that increased miR-29a not only alleviated HFD-induced body weight gain but also subcutaneous, visceral, and intestinal fat accumulation and hepatocellular steatosis in mice, as well as highlighting the role of miR -29a in regulation of NAFLD.
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The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species.
Hung-Yu Lin,Shao-Wen Weng,Yen-Hsiang Chang,Yu-Jih Su,Chih-Min Chang,Chia-Jen Tsai,Feng-Chih Shen,Jiin-Haur Chuang,Tsu-Kung Lin,Chia-Wei Liou,Ching-Yi Lin,Pei-Wen Wang +11 more
TL;DR: The causal role ofmtDYN proteins in regulating IR resulted from diabetes-susceptible mitochondrial haplogroup B4 is discovered and direct intervention to reverse profission in mtDYN provides a novel therapeutic strategy for IR and T2D.