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Hyuncheol Oh

Researcher at Wonkwang University

Publications -  201
Citations -  4215

Hyuncheol Oh is an academic researcher from Wonkwang University. The author has contributed to research in topics: Nitric oxide & Nitric oxide synthase. The author has an hindex of 34, co-authored 191 publications receiving 3528 citations. Previous affiliations of Hyuncheol Oh include UPRRP College of Natural Sciences.

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Protein tyrosine phosphatase 1B inhibitors from Morus root bark.

TL;DR: An organic layer prepared from the Chinese crude drug 'Sang-Bai-Pi' (Morus root bark) was studied in order to identify the inhibitory compounds for protein tyrosine phosphatase 1B (PTP1B).
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Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba.

TL;DR: Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether, which showed hepatoprotective effects with EC(50) values of 10.3 +/- 0.62 micro, on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
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Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326

TL;DR: An acinar morphogenesis inhibitor named fusarisetin A (1) that possesses both an unprecedented carbon skeleton and a new pentacyclic ring system has been identified from an in-house fractionated fungal library using a three-dimensional matrigel-induced acinar Morphogenesis assay system.
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Imperatorin, a furanocoumarin from Angelica dahurica (Umbelliferae), induces cytochrome c-dependent apoptosis in human promyelocytic leukaemia, HL-60 Cells.

TL;DR: Imperatorin, a biologically active furanocoumarin from the roots of Angelica dahurica (Umbelliferae), was found to induce apoptosis in human promyelocytic leukaemia, HL-60 cells and the cytochrome c/caspase-9 pathway was responsible for imperatorin-induced apoptosis.
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In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells.

TL;DR: Findings suggest that 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a major component of this crude drug, was found to exhibit in vitro growth-inhibiting effect on human hepatocellular carcinoma cell line, SK-HEP-1 cells.