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Dong Oh Moon
Researcher at Daegu University
Publications - 6
Citations - 199
Dong Oh Moon is an academic researcher from Daegu University. The author has contributed to research in topics: Cell growth & Cell culture. The author has an hindex of 4, co-authored 6 publications receiving 175 citations. Previous affiliations of Dong Oh Moon include Korea Research Institute of Bioscience and Biotechnology.
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Journal ArticleDOI
Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326
Jae-Hyuk Jang,Yukihiro Asami,Jun-Pil Jang,Su N.Ok Kim,Dong Oh Moon,Kee-Sun Shin,Daisuke Hashizume,Makoto Muroi,Tamio Saito,Hyuncheol Oh,Bo Yeon Kim,Hiroyuki Osada,Jong Seog Ahn +12 more
TL;DR: An acinar morphogenesis inhibitor named fusarisetin A (1) that possesses both an unprecedented carbon skeleton and a new pentacyclic ring system has been identified from an in-house fractionated fungal library using a three-dimensional matrigel-induced acinar Morphogenesis assay system.
Journal ArticleDOI
Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation
Osong Kwon,Nak Kyun Soung,N. R. Thimmegowda,Sook Jung Jeong,Jae-Hyuk Jang,Dong Oh Moon,Jongkyeong Chung,Kyung S. Lee,Yong Tae Kwon,Raymond L. Erikson,Jong Seog Ahn,Bo Yeon Kim +11 more
TL;DR: Treatment of the cells with antioxidants N-acetylcysteine (NAC) and glutathione (GSH) revealed that patulin induced ATF3 expression and apoptosis were dependent on ROS generation, suggesting EGR-1 and ATF3 as critical targets for the development of anti-cancer chemotherapeutics.
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Protuboxepin A, a marine fungal metabolite, inducing metaphase arrest and chromosomal misalignment in tumor cells
Yukihiro Asami,Jae-Hyuk Jang,Nak-Kyun Soung,Long He,Dong Oh Moon,Jong Won Kim,Hyuncheol Oh,Makoto Muroi,Hiroyuki Osada,Bo Yeon Kim,Jong Seog Ahn +10 more
TL;DR: The mechanism by which protuboxepin A induces cancer cell growth inhibition, round-up morphology, M phase arrest, and an increase in the subG(1) population in tumor cells in a dose dependent manner are elucidated.
Journal ArticleDOI
Violaceols function as actin inhibitors inducing cell shape elongation in fibroblast cells.
Yukihiro Asami,Jae-Hyuk Jang,Hyuncheol Oh,Jae Hak Sohn,Jong Won Kim,Dong Oh Moon,Osong Kwon,Makoto Kawatani,Hiroyuki Osada,Bo Yeon Kim,Jong Seog Ahn +10 more
TL;DR: A novel function of violaceol-I and -II is identified as actin inhibitors, which may give researchers new insights into the role of actin in tumorigenesis and lead to the development of additional anti-tumor drugs.
Journal ArticleDOI
Correction to Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326
Jae-Hyuk Jang,Yukihiro Asami,Jun-Pil Jang,Sun-Ok Kim,Dong Oh Moon,Kee-Sun Shin,Daisuke Hashizume,Makoto Muroi,Tamio Saito,Hyuncheol Oh,Bo Yeon Kim,Hiroyuki Osada,Jong Seog Ahn +12 more