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I. A. Menon
Researcher at University of Toronto
Publications - 21
Citations - 899
I. A. Menon is an academic researcher from University of Toronto. The author has contributed to research in topics: Melanin & Corneal endothelium. The author has an hindex of 13, co-authored 20 publications receiving 869 citations.
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Journal ArticleDOI
Eumelanins and pheomelanins: characterization by electron spin resonance spectroscopy
TL;DR: Several natural eumelanins and pheomelanin have been characterized and shown to be copolymers and a simple parameterization of the spectra allows estimation of the relative amounts of dopa melanin and cysteinyldopa melanin in mixtures and of dopas incorporated intoCopolymers.
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Novel free radicals in synthetic and natural pheomelanins: distinction between dopa melanins and cysteinyldopa melanins by ESR spectroscopy
R. C. Sealy,James S. Hyde,Christopher C. Felix,I. A. Menon,Giuseppe Prota,Harold M. Swartz,S. Persad,H. F. Haberman +7 more
TL;DR: Synthetic pheomelanins from enzymic oxidation of the 3,4-dihydroxyphenylalanine (dopa) derivative 5-S-cysteinyldopa have been examined by ESR spectroscopy and strongly suggest an o-semiquinonimine structure.
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Reaction of superoxide anions with melanins: electron spin resonance and spin trapping studies.
Witold Korytowski,Witold Korytowski,Balaraman Kalyanaraman,I. A. Menon,Tadeusz Sarna,Tadeusz Sarna,R. C. Sealy +6 more
TL;DR: It was found that the xanthine-xanthine oxidase system is not suitable for studying the reaction of superoxide with melanin, as the enzymatic activity of xanthin oxidase is considerably inhibited by melanin.
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Photosensitization of melanins: a comparative study
T. Sarna,I. A. Menon,R. C. Sealy +2 more
TL;DR: A significant enhancement in the rates of free radical production and oxygen consumption was found in all systems when sensitizer was present and the largest effects were found with cysteinyldopa melanin and effects on pheomelanin were shown to be greater than on eumelanins.
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COMPARISON OF THE EFFECTS OF UV‐VISIBLE IRRADIATION OF MELANINS and MELANIN‐HEMATOPORPHYRIN COMPLEXES FROM HUMAN BLACK and RED HAIR
TL;DR: Comparative studies on the formation of superoxide during the irradiation of the melanins isolated from human black and red hair (BHM and RHM, respectively) showed that no superoxide formation could be detected in the case of the BHM, whereas the formationOf superoxide During the irradiated of RHM could be definitely demonstrated.