W
Witold Korytowski
Researcher at Jagiellonian University
Publications - 82
Citations - 3798
Witold Korytowski is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Lipid peroxidation & Nitric oxide. The author has an hindex of 34, co-authored 78 publications receiving 3557 citations. Previous affiliations of Witold Korytowski include Medical College of Wisconsin.
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Journal ArticleDOI
Blue Light-induced Reactivity of Retinal Age Pigment IN VITRO GENERATION OF OXYGEN-REACTIVE SPECIES
Malgorzata Barbara Rozanowska,J. Jarvis-Evans,Witold Korytowski,Michael E. Boulton,Janice M. Burke,T. Sarna +5 more
TL;DR: It is postulate that lipofuscin is a potential photosensitizer that may increase the risk of retinal photodamage and contribute to the development of age-related maculopathy.
Journal ArticleDOI
Loss of melanin from human RPE with aging: possible role of melanin photooxidation.
Tadeusz Sarna,Janice M. Burke,Witold Korytowski,Malgorzata Barbara Rozanowska,Christine M. B. Skumatz,Agnieszka Zaręba,Mariusz Zareba +6 more
TL;DR: The content of melanin in RPE cells undergoes an age-related change to which photo-oxidation may contribute, raising the question of whether age- related changes in melanin reduce the photoprotective role of the pigment in aging R PE cells.
Journal ArticleDOI
Photoinduced generation of hydrogen peroxide and hydroxyl radicals in melanins
TL;DR: Evidence for metal‐ion dependent formation of hydroxyl radicals during photooxidation of melanin pigments was obtained using electron spin resonance‐spin trapping procedures and superoxide dismutase increased the rate of formation of hydroxy radicals in the system.
Journal ArticleDOI
Bleaching of melanin pigments. Role of copper ions and hydrogen peroxide in autooxidation and photooxidation of synthetic dopa-melanin.
Witold Korytowski,T. Sarna +1 more
TL;DR: The data indicate that bleaching of melanin is a complex process with two distinct stages, reversible oxidation of the hydroquinone moieties of melan in followed by irreversible reactions of the monomers that lead to degradation of the melanin polymer.
Journal ArticleDOI
Blue Light-Induced Reactivity of Retinal Age Pigment: In Vitro Generation of Oxygen-Reactive Species
Malgorzata Barbara Rozanowska,J. Jarvis-Evans,Witold Korytowski,Michael E. Boulton,Janice M. Burke,T. Sarna +5 more
TL;DR: It is postulate that lipofuscin is a potential photosensitizer that may increase the risk of retinal photodamage and contribute to the development of age-related maculopathy.