H
Harold M. Swartz
Researcher at Dartmouth College
Publications - 402
Citations - 14030
Harold M. Swartz is an academic researcher from Dartmouth College. The author has contributed to research in topics: Electron paramagnetic resonance & Oxygen. The author has an hindex of 61, co-authored 394 publications receiving 13279 citations. Previous affiliations of Harold M. Swartz include Ohio State University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
Jeffrey M. Arbeit,J. Martin Brown,K.S.Clifford Chao,J. Donald Chapman,William C. Eckelman,Anthony Fyles,Amato J. Giaccia,Richard P. Hill,Cameron J. Koch,Murali C. Krishna,Kenneth A. Krohn,Jason S. Lewis,Ralph P. Mason,Giovanni Melillo,Anwar R. Padhani,Garth Powis,Joseph G. Rajendran,Richard C Reba,Simon P. Robinson,Gregg L. Semenza,Harold M. Swartz,Peter Vaupel,David J. Yang,James L. Tatum +23 more
TL;DR: Recommendations are yielded on using hypoxia measurement to identify patients who would respond best to radiation therapy, which would improve treatment planning and represent a narrow focus, as hypoxIA measurement might also prove useful in drug development and in increasing the understanding of tumor biology.
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Lithium phthalocyanine: a probe for electron paramagnetic resonance oximetry in viable biological systems.
K. J. Liu,P. Gast,M. Moussavi,Shong-Wan Norby,N. Vahidi,Tadeusz Walczak,M Wu,Harold M. Swartz +7 more
TL;DR: Physicochemically LiPc is very stable; its response to pO2 does not change with conditions and environments likely to occur in viable biological systems; these characteristics provide the sensitivity, accuracy, and range to measure physiologically and pathologically pertinent O2 tensions.
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Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite.
TL;DR: The data suggest that superoxide and H2O2 are the predominant reactive species produced by endothelial cells after arsenite exposures that stimulate cell signaling and activate transcription factors.
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Trapping of free radicals with direct in vivo EPR detection: a comparison of 5,5-dimethyl-1-pyrroline-N-oxide and 5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide as spin traps for HO* and SO4*-.
TL;DR: In mice treatment with 5-aminolevulinic acid and Fe3+ resulted in detection of adducts of hydroxyl radicals (HO*), but only with use of DEPMPO, which seems to be the first direct in vivo EPR detection ofHydroxyl radical adduction.
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Impact of Mouse Strain Differences in Innate Hindlimb Collateral Vasculature
Armin Helisch,Shawn Wagner,Nadeem Khan,Mary Drinane,Swen Wolfram,Matthias Heil,Tibor Ziegelhoeffer,Ulrike Brandt,Justin D. Pearlman,Harold M. Swartz,Wolfgang Schaper +10 more
TL;DR: Genetic differences in preexistent collateral vasculature can profoundly affect outcome and milieu for compensatory collateral artery growth after femoral artery occlusion.