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In-Kyu Yoon
Researcher at International Vaccine Institute
Publications - 131
Citations - 6353
In-Kyu Yoon is an academic researcher from International Vaccine Institute. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 41, co-authored 127 publications receiving 5339 citations. Previous affiliations of In-Kyu Yoon include United States Department of the Army & Walter Reed Army Institute of Research.
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Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial
Maria Rosario Capeding,Ngoc Huu Tran,Sri Rezeki Hadinegoro,Hussain Imam Muhammad Ismail,Tawee Chotpitayasunondh,Mary Noreen Chua,Chan Quang Luong,Kusnandi Rusmil,Dewa Nyoman Wirawan,Revathy Nallusamy,Punnee Pitisuttithum,Usa Thisyakorn,In-Kyu Yoon,Diane van der Vliet,Edith Langevin,Thelma Laot,Yanee Hutagalung,Carina Frago,Mark Boaz,T. Anh Wartel,Nadia Tornieporth,Melanie Saville,Alain Bouckenooghe +22 more
TL;DR: The findings show that dengue vaccine is efficacious when given as three injections at months 0, 6, and 12 to children aged 2-14 years in endemic areas in Asia, and has a good safety profile.
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Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity
Nicholas G. Reich,Nicholas G. Reich,Sourya Shrestha,Aaron A. King,Aaron A. King,Pejman Rohani,Pejman Rohani,Justin Lessler,Siripen Kalayanarooj,In-Kyu Yoon,Robert V. Gibbons,Donald S. Burke,Derek A. T. Cummings +12 more
TL;DR: This is the first quantitative evidence that short-term cross-protection exists since human experimental infection studies performed in the 1950s and will impact strategies for designing dengue vaccine studies, future multi-Strain modelling efforts, and the understanding of evolutionary pressures in multi-strain disease systems.
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Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006.
Jessica R. Fried,Robert V. Gibbons,Siripen Kalayanarooj,Stephen J. Thomas,Anon Srikiatkhachorn,In-Kyu Yoon,Richard G. Jarman,Sharone Green,Alan L. Rothman,Derek A. T. Cummings +9 more
TL;DR: DENV-2 appears to be marginally associated with more severe dengue disease as evidenced by a significant association with DHF grade I when compared to DENV-1, and non-significant trends with other grades of DHF are found.
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Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973 to 2010
In-Kyu Yoon,A. Nisaluk,S. Kalayanarooj,Chonticha Klungthong,Butsaya Thaisomboonsuk,P. Bhoomiboonchoo,Robert V. Gibbons +6 more
TL;DR: The findings illustrate the uniqueness of each serotype in producing epidemics and severe disease and underscore the importance of long-term surveillance of dengue serotypes in understanding the epidemiology of these viruses.
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Detection of Zika Virus Infection in Thailand, 2012–2014
Rome Buathong,Laura Hermann,Butsaya Thaisomboonsuk,Wiriya Rutvisuttinunt,Chonticha Klungthong,Piyawan Chinnawirotpisan,Wudtichai Manasatienkij,Ananda Nisalak,Stefan Fernandez,In-Kyu Yoon,Passakorn Akrasewi,Tanarak Plipat +11 more
TL;DR: Seven cases of acute ZIKV infection in Thai residents across the country confirmed by molecular or serological testing including sequence data provide evidence that ZikV is widespread throughout Thailand.