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Indraneel Ghosh
Researcher at University of Arizona
Publications - 86
Citations - 4378
Indraneel Ghosh is an academic researcher from University of Arizona. The author has contributed to research in topics: DNA & Phosphorylation. The author has an hindex of 34, co-authored 84 publications receiving 4112 citations. Previous affiliations of Indraneel Ghosh include Weizmann Institute of Science & Yale University.
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Antiparallel Leucine Zipper-Directed Protein Reassembly: Application to the Green Fluorescent Protein
TL;DR: The sequences of the designed leucine zippers, NZ and CZ, are ALKKELQANKKELAQLKWELQALKKELAQ and EQLEKKLQALEKKLAQLEWKNQALEkkLAQ, respectively.
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Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism.
Thomas J. Magliery,Christopher Wilson,Weilan Pan,Dennis Mishler,Indraneel Ghosh,and Andrew D. Hamilton,Lynne Regan +6 more
TL;DR: The general utility of the screen for detecting protein-protein interactions based on reassembly of dissected fragments of green fluorescent protein fused to interacting peptides is demonstrated and insight into the positional inequivalence of stabilizing interactions in antiparallel coiled coils is given.
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DCX, a new mediator of the JNK pathway
Amos Gdalyahu,Indraneel Ghosh,Talia Levy,Tamar Sapir,Sivan Sapoznik,Yael Fishler,David Azoulai,Orly Reiner +7 more
TL;DR: It is demonstrated that DCX is a substrate of JNK and interacts with both c‐Jun N‐terminal kinase (JNK) and JNK interacting protein (JIP), and the localization of this signaling module in the developing brain suggests its functionality in migrating neurons.
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Split-protein systems: beyond binary protein-protein interactions.
TL;DR: Recent advances in engineering split-protein systems that allow for the rapid detection of ternary protein complexes, small molecule inhibitors, as well as a variety of macromolecules including nucleic acids, poly(ADP) ribose, and iron sulfur clusters are presented.
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Selective amplification by auto- and cross-catalysis in a replicating peptide system
TL;DR: The ability of this four-component peptide system that is capable of auto- and cross-catalysis and allows for the selective amplification of one or more of the products by changing the reaction conditions supports the suggestion that self-replicating peptides may have played a role in the origin of life.