Journal•ISSN: 1367-5931
Current Opinion in Chemical Biology
Elsevier BV
About: Current Opinion in Chemical Biology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Biology. It has an ISSN identifier of 1367-5931. Over the lifetime, 2731 publications have been published receiving 223637 citations.
Topics: Medicine, Biology, Chemistry, Drug discovery, Chemical biology
Papers published on a yearly basis
Papers
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TL;DR: This review focuses on those parameters that affect image signal and background during in vivo imaging with near-infrared light and exogenous contrast agents.
2,470 citations
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TL;DR: It is demonstrated that bulk water structure is not central to the Hofmeister effect, and models are being developed that depend upon direct ion-macromolecule interactions as well as interactions with water molecules in the first hydration shell of the macromolecules.
1,786 citations
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TL;DR: Carbon nanotubes have emerged as a new alternative and efficient tool for transporting and translocating therapeutic molecules and hold great potential in the field of nanobiotechnology and nanomedicine.
1,783 citations
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TL;DR: Recent trends in the field include the more selective delivery and/or activation of cisplatin-related prodrugs and the discovery of new non-covalent interactions with the classical target, DNA.
1,164 citations
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TL;DR: This review explores the concept of using privileged scaffolds to identify biologically active compounds through building chemical libraries by revealing through four selected examples the present state of the art in privileged scaffold library synthesis.
1,160 citations