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Indu G. Poornima
Researcher at Allegheny General Hospital
Publications - 24
Citations - 1249
Indu G. Poornima is an academic researcher from Allegheny General Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 15 publications receiving 1158 citations.
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Journal ArticleDOI
Diabetic Cardiomyopathy The Search for a Unifying Hypothesis
TL;DR: The recent recognition that diabetes involves more than abnormal glucose homeostasis provides important new opportunities to examine and understand the impact of complex metabolic disturbances on cardiac structure and function.
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Direct Effects of Glucagon-Like Peptide-1 on Myocardial Contractility and Glucose Uptake in Normal and Postischemic Isolated Rat Hearts
Tingcun Zhao,Pratik Parikh,Siva Bhashyam,Hakki Bolukoglu,Indu G. Poornima,You-Tang Shen,Richard P. Shannon +6 more
TL;DR: GLP-1 has direct effects on the normal heart, reducing contractility, but increasing myocardial glucose uptake through a non-Akt-1-dependent mechanism, distinct from the actions of insulin.
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Chronic Glucagon-Like Peptide-1 Infusion Sustains Left Ventricular Systolic Function and Prolongs Survival in the Spontaneously Hypertensive, Heart Failure–Prone Rat
Indu G. Poornima,Suzanne B. Brown,Siva Bhashyam,Pratik Parikh,Hakki Bolukoglu,Richard P. Shannon +5 more
TL;DR: In this article, Glucagon-like peptide-1 (GLP-1) treatment leads to short-term improvements in myocardial function in ischemic and nonischemic cardiomyopathy.
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Anatomical factors triggering platypnea-orthodeoxia in adults.
TL;DR: A case series of patients presenting with dyspnea and orthodeoxia who developed right to left shunting as a result of associated anatomical changes that occur with aging such as tortuosity and elongation of the aorta are reported.
Journal ArticleDOI
The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy.
Lazaros A. Nikolaidis,Indu G. Poornima,Pratik Parikh,Megan Magovern,You-tang Shen,Richard P. Shannon +5 more
TL;DR: At doses inducing comparable heart rate reductions, short-term treatment with carvedilol had superior hemodynamic and metabolic effects compared with metoprolol CR/XL, suggesting important advantages of blocking all three adrenergic receptor subtypes in DCM.