Ingela Turesson

TL;DR: When given with prednisone, treatment with docetaxel every three weeks led to superior survival and improved rates of response in terms of pain, serum PSA level, and quality of life, as compared with mitoxantrone plusprednisone.

TL;DR: Results implicate p38 in organization of new vessels and suggest that p38 is an essential regulator of FGF-2–driven angiogenesis, which is suggested to be an essential regulation of growth factor–dependent cellular functions.

TL;DR: The initial results of a study aimed at establishing whether a direct relationship exists between cellular radiosensitivity and tissue response suggest that cellular sensitivity might form the basis for the development of an assay system capable of predicting late normal tissue effects to curative radiotherapy, which might allow dose escalation in some patients.

TL;DR: A method to measure the relative amount of DNA double strand breaks by detecting gamma H2AX foci in patients exposed to radiotherapy is established and has the potential to predict individual radiosensitivity.

TL;DR: It is hoped that the definitions and terminology proposed here will aid communication in the field of predictive testing of normal tissue radiosensitivity, as well as a simple terminology for describing normal tissue reactions in patients having radiotherapy.