Ingrid Sadler-Riggleman

TL;DR: Observations suggest environmentally induced epigenetic transgenerational inheritance of disease is a critical aspect of disease etiology, toxicology and evolution that needs to be considered.

TL;DR: All three different epigenetic processes were concurrently altered as DDT induced the epigenetic transgenerational inheritance of sperm epimutations, demonstrating all three epigenetic Processes are involved in transGenerational inheritance.

TL;DR: It is proposed glyphosate can induce the transgenerational inheritance of disease and germline (e.g. sperm) epimutations through differential DNA methylation regions (DMRs).

TL;DR: Investigation of the vinclozolin-induced concurrent alterations of a number of different epigenetic factors, including DNA methylation, ncRNA, and histone retention in rat sperm shows that the three different types of epimutations are involved and integrated in the mediation of the epigenetic transgenerational inheritance phenomenon.

TL;DR: Observations indicate that although atrazine does not promote disease in the directly exposed F1 generation, it does have the capacity to promote the epigenetic transgenerational inheritance of disease.